Resistance of gram-negative bacteria to current antibacterial agents and approaches to resolve it

Z Breijyeh, B Jubeh, R Karaman - Molecules, 2020 - mdpi.com
Antimicrobial resistance represents an enormous global health crisis and one of the most
serious threats humans face today. Some bacterial strains have acquired resistance to …

Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants of Neisseria gonorrhoeae

B Mlynarczyk-Bonikowska, C Kowalewski… - International Journal of …, 2022 - mdpi.com
The paper presents various issues related to the increasing drug resistance of Neisseria
gonorrhoeae and the occurrence and spread of multidrug-resistant clones. One of the most …

Current state of knowledge regarding who high priority pathogens—Resistance mechanisms and proposed solutions through candidates such as essential oils: A …

M Romanescu, C Oprean, A Lombrea… - International journal of …, 2023 - mdpi.com
Combating antimicrobial resistance (AMR) is among the 10 global health issues identified
by the World Health Organization (WHO) in 2021. While AMR is a naturally occurring …

Azithromycin resistant gonococci: a literature review

A Derbie, D Mekonnen, Y Woldeamanuel… - … resistance & infection …, 2020 - Springer
Objective Gonorrhea is the second most common sexually transmitted bacterial infection
(STI) next to Chlamydia. Untreated cases could results in major complications like pelvic …

Multidrug-resistant Neisseria gonorrhoeae infection in heterosexual men with reduced susceptibility to ceftriaxone, first report in Thailand

N Kueakulpattana, DL Wannigama, S Luk-In… - Scientific Reports, 2021 - nature.com
The global rapid emergence of azithromycin/ceftriaxone resistant Neisseria gonorrhoeae
threatens current recommend azithromycin/ceftriaxone dual therapy for gonorrhea to ensure …

Pelvic inflammatory disease in the adolescent and young adult: An update

DE Greydanus, MD Cabral, DR Patel - Disease-a-Month, 2022 - Elsevier
Pelvic inflammatory disease (PID) is an infection of the female upper genital tract that is
typically polymicrobial with classic core involvement of Neisseria gonorrhoeae and/or …

Imipridone anticancer compounds ectopically activate the ClpP protease and represent a new scaffold for antibiotic development

S Jacques, AM van der Sloot, C C. Huard… - Genetics, 2020 - academic.oup.com
The imipridones ONC201 and ONC212 selectively kill cancer cells and have been ascribed
multiple mechanisms-of-action. Genome-wide CRISPR knockout screens revealed that loss …

Bacteriophages and the one health approach to combat multidrug resistance: is this the way?

M Garvey - Antibiotics, 2020 - mdpi.com
Antimicrobial resistance necessitates action to reduce and eliminate infectious disease,
ensure animal and human health, and combat emerging diseases. Species such as …

First nationwide antimicrobial susceptibility surveillance for Neisseria gonorrhoeae in Brazil, 2015–16

ML Bazzo, L Golfetto, PC Gaspar… - Journal of …, 2018 - academic.oup.com
Objectives Gonorrhoea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are
major public health concerns globally. Enhanced AMR surveillance for gonococci is …

Preclinical efficacy of a lipooligosaccharide peptide mimic candidate gonococcal vaccine

S Gulati, MW Pennington, A Czerwinski, D Carter… - Mbio, 2019 - Am Soc Microbiol
The global spread of multidrug-resistant strains of Neisseria gonorrhoeae constitutes a
public health emergency. With limited antibiotic treatment options, there is an urgent need …