Identification and treatment of latent tuberculosis infection (LTBI) can substantially reduce
the risk of developing active disease. However, there is no diagnostic gold standard for LTBI …

The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete
pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) …

New approaches to control the spread of tuberculosis (TB) are needed, including tools to
predict development of active TB from latent TB infection (LTBI). Recent studies have …

Background Novel skin-based tests for tuberculosis infection might present suitable
alternatives to current tests; however, diagnostic performance of new tests compared with …

Background Given the current lack of effective vaccines against TB, the accuracy of
screening tests for determining or excluding latent TB infection (LTBI) is decisive in effective …

Background. The diagnostic value of interferon-γ release assays (IGRAs) for active
tuberculosis in low-and middle-income countries is unclear. Methods. We searched multiple …

BACKGROUND. The identification and treatment of individuals with tuberculosis (TB) is a
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease …

Tuberculosis (TB) is a possible complication of solid organ and hematopoietic stem cell
transplantation. The identification of candidates for preventive chemotherapy is an effective …

Tuberculosis (TB) remains an important problem among children in the United States and
throughout the world. Although diagnosis and treatment of infection with Mycobacterium …

Identifying latently infected individuals is crucial for the elimination of tuberculosis (TB). We
evaluated for the first time the performance of a new type of interferon-γ release assay …