Inhibition of epithelial to mesenchymal transition by E-cadherin up-regulation via repression of slug transcription and inhibition of E-cadherin degradation: dual role of …
A Adhikary, S Chakraborty, M Mazumdar… - Journal of Biological …, 2014 - ASBMB
The evolution of the cancer cell into a metastatic entity is the major cause of death in patients
with cancer. It has been acknowledged that aberrant activation of a latent embryonic …
with cancer. It has been acknowledged that aberrant activation of a latent embryonic …
Curcumin enhances the efficacy of chemotherapy by tailoring p65NFκB-p300 cross-talk in favor of p53-p300 in breast cancer
GS Sen, S Mohanty, DMS Hossain… - Journal of Biological …, 2011 - ASBMB
Breast cancer cells often develop multiple mechanisms of drug resistance during tumor
progression, which is the major reason for the failure of breast cancer therapy. High …
progression, which is the major reason for the failure of breast cancer therapy. High …
[HTML][HTML] Thymosin β4 inhibits TNF-α-induced NF-κB activation, IL-8 expression, and the sensitizing effects by its partners PINCH-1 and ILK
P Qiu, MK Wheater, Y Qiu, G Sosne - The FASEB Journal, 2011 - ncbi.nlm.nih.gov
The mechanisms by which thymosin β 4 (Tβ 4) regulates the inflammatory response to injury
are poorly understood. Previously, we demonstrated that ectopic Tβ 4 treatment inhibits …
are poorly understood. Previously, we demonstrated that ectopic Tβ 4 treatment inhibits …
Gene regulation by SMAR1: Role in cellular homeostasis and cancer
Changes in the composition of nuclear matrix associated proteins contribute to alterations in
nuclear structure, one of the major phenotypes of malignant cancer cells. The malignancy …
nuclear structure, one of the major phenotypes of malignant cancer cells. The malignancy …
Mapping of scaffold/matrix attachment regions in human genome: a data mining exercise
Scaffold/matrix attachment regions (S/MARs) are DNA elements that serve to
compartmentalize the chromatin into structural and functional domains. These elements are …
compartmentalize the chromatin into structural and functional domains. These elements are …
Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
K Singh, S Matsuyama, JA Drazba, A Almasan - Autophagy, 2012 - Taylor & Francis
Autophagy regulates cell survival and cell death upon various cellular stresses, yet the
molecular signaling events involved are not well defined. Here, we established the function …
molecular signaling events involved are not well defined. Here, we established the function …
A polyherbal formulation, HC9 regulated cell growth and expression of cell cycle and chromatin modulatory proteins in breast cancer cell lines
S Suryavanshi, A Choudhari, P Raina… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance HC9, a polyherbal formulation, is based upon a traditional
Ayurvedic formulation, Stanya Shodhana Kashaya (SSK, having 10 plant materials) …
Ayurvedic formulation, Stanya Shodhana Kashaya (SSK, having 10 plant materials) …
C/EBPβ enhances NF–κB-associated signalling by reducing the level of IκB-α
C Cappello, A Zwergal, S Kanclerski, SC Haas… - Cellular signalling, 2009 - Elsevier
NF–κB and C/EBPβ proteins are involved in the regulation of genes which play a role in
inflammation, immunity and malignant processes. The present study focuses on the question …
inflammation, immunity and malignant processes. The present study focuses on the question …
Reversible induction of translational isoforms of p53 in glucose deprivation
Tumor suppressor protein p53 is a master transcription regulator, indispensable for
controlling several cellular pathways. Earlier work in our laboratory led to the identification of …
controlling several cellular pathways. Earlier work in our laboratory led to the identification of …
RING finger protein TOPORS modulates the expression of tumor suppressor SMAR1 in colorectal cancer via the TLR4‐TRIF pathway
TOP1‐binding arginine/serine‐rich protein (TOPORS), a really interesting new gene finger
protein, has the ability to bind to a palindromic consensus DNA sequence that enables it to …
protein, has the ability to bind to a palindromic consensus DNA sequence that enables it to …