Epigenetics in the uterine environment: how maternal diet and ART may influence the epigenome in the offspring with long-term health consequences
I Peral-Sanchez, B Hojeij, DA Ojeda… - Genes, 2021 - mdpi.com
The societal burden of non-communicable disease is closely linked with environmental
exposures and lifestyle behaviours, including the adherence to a poor maternal diet from the …
exposures and lifestyle behaviours, including the adherence to a poor maternal diet from the …
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
CL Relton, G Davey Smith - International journal of …, 2012 - academic.oup.com
The burgeoning interest in the field of epigenetics has precipitated the need to develop
approaches to strengthen causal inference when considering the role of epigenetic …
approaches to strengthen causal inference when considering the role of epigenetic …
Environmental exposures around conception: developmental pathways leading to lifetime disease risk
TP Fleming, C Sun, O Denisenko, L Caetano… - International Journal of …, 2021 - mdpi.com
Environment around conception can influence the developmental programme with lasting
effects on gestational and postnatal phenotype and with consequences for adult health and …
effects on gestational and postnatal phenotype and with consequences for adult health and …
Maternal peri-conceptional undernourishment perturbs offspring sperm methylome
P Toschi, E Capra, DA Anzalone, B Lazzari… - …, 2020 - rep.bioscientifica.com
The genotype of an organism is stable throughout its life; however, its epigenome is dynamic
and can be altered in response to environmental factors, such as diet. Inheritance of …
and can be altered in response to environmental factors, such as diet. Inheritance of …
Epigenetics and developmental programming in ruminants: Long-term impacts on growth and development
Human epidemiological studies worldwide have provided convincing support for the
concept of developmental programming. The concept of developmental programming was …
concept of developmental programming. The concept of developmental programming was …
Developmental conditioning of the vasculature
GF Clough - Comprehensive Physiology, 2011 - Wiley Online Library
There is increasing evidence from epidemiological and experimental animal studies that the
early life environment, of which nutrition is a key component, acts through developmental …
early life environment, of which nutrition is a key component, acts through developmental …
An earlier rise in systemic progesterone and increased progesterone in the uterine vein during early pregnancy are associated with enhanced embryonic survival in …
AR O'Connell, PR Hurst, GH Davis, KP McNatty… - Theriogenology, 2013 - Elsevier
Improved livestock production efficiency through greater embryonic survival (ES) is of
economic and animal welfare benefit. Physiological characterization of animals that are …
economic and animal welfare benefit. Physiological characterization of animals that are …
Hosting the preimplantation embryo: potentials and limitations of different approaches for analysing embryo–endometrium interactions in cattle
SE Ulbrich, E Wolf, S Bauersachs - Reproduction, Fertility and …, 2012 - CSIRO Publishing
Ongoing detailed investigations into embryo–maternal communication before implantation
reveal that during early embryonic development a plethora of events are taking place …
reveal that during early embryonic development a plethora of events are taking place …
Programmed for sex: Nutrition–reproduction relationships from an inter-generational perspective
RM Sharpe - Reproduction, 2018 - rep.bioscientifica.com
Reproduction is our biological reason for being. Our physiology has been shaped via
countless millennia of evolution with this one purpose in mind, so that at birth we are …
countless millennia of evolution with this one purpose in mind, so that at birth we are …