Current research therapeutic strategies for Alzheimer's disease treatment

J Folch, D Petrov, M Ettcheto, S Abad… - Neural …, 2016 - Wiley Online Library
Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …

Role of environmental contaminants in the etiology of Alzheimer's disease: a review

M Yegambaram, B Manivannan… - Current Alzheimer …, 2015 - ingentaconnect.com
Alzheimer's dis ease (AD) is a leading cause of mortality in the developed world with 70%
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …

Role of environmental pollutants in Alzheimer's disease: a review

RH Mir, G Sawhney, FH Pottoo, R Mohi-Ud-Din… - … Science and Pollution …, 2020 - Springer
Neurodegenerative disorders are commonly erratic influenced by various factors including
lifestyle, environmental, and genetic factors. In recent observations, it has been …

[HTML][HTML] Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals

V Berti, J Murray, M Davies, N Spector, WH Tsui… - The Journal of nutrition …, 2015 - Elsevier
Objectives Epidemiological evidence linking diet, one of the most important modifiable
lifestyle factors, and risk of Alzheimer's disease (AD) is rapidly increasing. However, there is …

Nutrition and prevention of Alzheimer's dementia

A Swaminathan, GA Jicha - Frontiers in aging neuroscience, 2014 - frontiersin.org
A nutritional approach to prevent, slow, or halt the progression of disease is a promising
strategy that has been widely investigated. Much epidemiologic data suggests that …

Blood-Brain Barrier and Cognitive Function

AM Zăgrean, B Ianosi, C Sonea, I Opris… - The Physics of the Mind …, 2017 - Springer
The blood-brain barrier (BBB) is the highly specialized and selective crossing area between
blood and brain, essential for brain homeostasis and functioning, formed by the endothelial …

Characterization of biometal profiles in neurological disorders

S Pfaender, AM Grabrucker - Metallomics, 2014 - academic.oup.com
Many neurodegenerative and neuropsychiatric disorders have been reported to coincide
with the dysregulation of metal ions in the body and central nervous system. However, in …

Impact of micronutrients and nutraceuticals on cognitive function and performance in Alzheimer's disease

L Guarnieri, F Bosco, A Leo, R Citraro, E Palma… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a major global health problem today and is the most common
form of dementia. AD is characterized by the formation of β-amyloid (Aβ) plaques and …

Selenomethionine ameliorates cognitive decline, reduces tau hyperphosphorylation, and reverses synaptic deficit in the triple transgenic mouse model of Alzheimer's …

G Song, Z Zhang, L Wen, C Chen, Q Shi… - Journal of …, 2014 - content.iospress.com
Disruption of the intracellular balance between free radicals and the antioxidant system is a
prominent and early feature in the neuropathology of Alzheimer's disease (AD). Selenium, a …

Association between cognitive function and supplementation with omega-3 PUFAs and other nutrients in≥ 75 years old patients: a randomized multicenter study

J Baleztena, M Ruiz-Canela, C Sayon-Orea, M Pardo… - PLoS …, 2018 - journals.plos.org
A few studies have assessed the association between omega-3 polyunsaturated fatty acids
(n-3 PUFA) and cognitive impairment (CI) in very old adults. The aim of this study was to …