[HTML][HTML] Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention

SL Poon, JR McPherson, P Tan, BT Teh, SG Rozen - Genome medicine, 2014 - Springer
Exposure to environmental mutagens is an important cause of human cancer, and measures
to reduce mutagenic and carcinogenic exposures have been highly successful at controlling …

[HTML][HTML] Occupational exposures and colorectal cancers: a quantitative overview of epidemiological evidence

E Oddone, C Modonesi, G Gatta - World Journal of …, 2014 - ncbi.nlm.nih.gov
A traditional belief widespread across the biomedical community was that dietary habits and
genetic predisposition were the basic factors causing colorectal cancer. In more recent …

[HTML][HTML] The importance of evaluating specific myeloid malignancies in epidemiological studies of environmental carcinogens

KA Mundt, LD Dell, P Boffetta, EM Beckett, HN Lynch… - BMC cancer, 2021 - Springer
Introduction Although myelodysplastic syndrome (MDS), acute myeloid leukemia (AML),
myeloproliferative neoplasms (MPN)–including chronic myeloid leukemia (CML)–and …

Use of job-exposure matrices to estimate occupational exposure to pesticides: A review

C Carles, G Bouvier, P Lebailly, I Baldi - Journal of Exposure Science & …, 2017 - nature.com
The health effects of pesticides have been extensively studied in epidemiology, mainly in
agricultural populations. However, pesticide exposure assessment remains a key …

[HTML][HTML] Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde …

KA Mundt, PR Gentry, LD Dell, JV Rodricks… - Regulatory Toxicology …, 2018 - Elsevier
Abstract Shortly after the International Agency for Research on Cancer (IARC) determined
that formaldehyde causes leukemia, the United States Environmental Protection Agency …

The population-based occupational and environmental health prospective cohort study (AMIGO) in the Netherlands

P Slottje, CJ Yzermans, JC Korevaar, M Hooiveld… - BMJ open, 2014 - bmjopen.bmj.com
Purpose Occupational and environmental exposures remain important modifiable risk
factors of public health. Existing cohort studies are often limited by the level of detail of data …

Using mechanistic information to support evidence integration and synthesis: A case study with inhaled formaldehyde and leukemia

R Gentry, CM Thompson, A Franzen… - Critical Reviews in …, 2020 - Taylor & Francis
Formaldehyde is one of the most comprehensively studied chemicals, with over 30 years of
research focused on understanding the development of cancer following inhalation. The …

Interventional probability of causation (IPoC) with epidemiological and partial mechanistic evidence: benzene vs. formaldehyde and acute myeloid leukemia (AML)

LA Cox Jr, WJ Thompson, KA Mundt - Critical Reviews in …, 2024 - Taylor & Francis
Introduction Causal epidemiology for regulatory risk analysis seeks to evaluate how
removing or reducing exposures would change disease occurrence rates. We define …

[HTML][HTML] Occupational exposure to pesticides and chronic lymphocytic leukaemia in the MCC-Spain study

Y Benavente, L Costas, MM Rodríguez-Suarez… - International journal of …, 2020 - mdpi.com
We aimed to study the association between occupational exposure to pesticides and chronic
lymphocytic leukemia (CLL) in Spain. Occupational exposure to pesticides (four insecticides …

[HTML][HTML] Agent Orange Toxicity

H Danchi, RJ Chen - 2023 - europepmc.org
Objectives: Assess the historical relevance of Agent Orange and its impact on veterans.
Identify risk factors of Agent Orange and dioxin exposure. Evaluate and manage patients …