The emerging role of miRNAs in Merkel cell carcinoma pathogenesis: Signaling pathway crosstalk

NI Rizk, HM Midan, GK Helal, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an uncommon invasive form of skin cancer that typically
manifests as a nodule on the face, head, or neck that is flesh-colored or bluish-red in …

miRNAs driving diagnosis, prognosis and progression in Merkel cell carcinoma

TM Al-Noshokaty, MS Elballal, GK Helal… - … -Research and Practice, 2023 - Elsevier
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin malignancy with a high
recurrence commonly within two to three years of initial diagnosis. The incidence of MCC …

The interplay between toxoplasmosis and host miRNAs: Mechanisms and consequences

AS Doghish, MA Ali, MA Elrebehy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
Toxoplasmosis is one of the highly prevalent zoonotic diseases worldwide caused by the
parasite Toxoplasma gondii (T. gondii). The infection with T. gondii could pass unidentified …

Melodic maestros: Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of malignant pleural mesothelioma

MA Abd-Elmawla, SSA Mageed… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly lethal form of pleural cancer
characterized by a scarcity of effective therapeutic interventions, resulting in unfavorable …

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease

NM Abdelmaksoud, AAM Sallam, AI Abulsoud… - … -Research and Practice, 2024 - Elsevier
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …

The role of miRNAs in multiple sclerosis pathogenesis, diagnosis, and therapeutic resistance

AS Doghish, O Elazazy, HH Mohamed… - … -Research and Practice, 2023 - Elsevier
In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

Investigating the regulatory role of miRNAs as silent conductors in the management of pathogenesis and therapeutic resistance of pancreatic cancer

AI Abulsoud, SS Elshaer, NM Abdelmaksoud… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) has the greatest mortality rate of all the main malignancies. Its
advanced stage and poor prognosis place it at the bottom of all cancer sites. Hence …

Smart/stimuli-responsive chitosan/gelatin and other polymeric macromolecules natural hydrogels vs. synthetic hydrogels systems for brain tissue engineering: A state …

HM El-Husseiny, EA Mady, AS Doghish… - International Journal of …, 2024 - Elsevier
Currently, there are no viable curative treatments that can enhance the central nervous
system's (CNS) recovery from trauma or illness. Bioengineered injectable smart/stimuli …

Decoding the role of miRNAs in oral cancer pathogenesis: A focus on signaling pathways

AS Doghish, AA El-Husseiny, EG Khidr… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is the predominant type originating in the head and neck region. The
incidence of OC is mostly associated with behavioral risk factors, including tobacco smoking …

Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer

AS Doghish, SS Elshaer, D Fathi, NI Rizk… - … -Research and Practice, 2024 - Elsevier
Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …