With industrialization and development in modern science enzymes and their applications
increased widely. There is always a hunt for new proficient enzymes with novel properties to …

Cold-active enzymes constitute an attractive resource for biotechnological applications.
Their high catalytic activity at temperatures below 25° C makes them excellent biocatalysts …

Novozym 435 (N435) is a commercially available immobilized lipase produced by
Novozymes. It is based on immobilization via interfacial activation of lipase B from Candida …

Enzymes found in nature have been exploited in industry due to their inherent catalytic
properties in complex chemical processes under mild experimental and environmental …

By far the largest proportion of the Earth's biosphere is comprised of organisms that thrive in
cold environments (psychrophiles). Their ability to proliferate in the cold is predicated on a …

The bulk of the Earth's biosphere is cold (eg 90% of the ocean's waters are≤ 5° C),
sustaining a broad diversity of microbial life. The permanently cold environments vary from …

Lipases are glycerol ester hydrolases that catalyze the hydrolysis of triglycerides to free fatty
acids and glycerol. Lipases catalyze esterification, interesterification, acidolysis, alcoholysis …

Chirality is a key factor in the safety and efficacy of many drug products and thus the
production of single enantiomers of drug intermediates and drugs has become important …

Enzyme stability is an important issue for protein engineers. Understanding how rigidity in
the active site affects protein kinetic stability will provide new insight into enzyme …

Protein function requires the folded protein form, but this form is unstable mainly because it
readily unfolds into a flexible, unstructured form. Protein folding is favored by burying of …