Clozapine-induced agranulocytosis/granulocytopenia: mechanis... : Current Opinion in
Hematology Clozapine-induced agranulocytosis/granulocytopenia: mechanisms and monitoring …

Clozapine is the only effective antipsychotic for treatment-resistant schizophrenia but
remains widely under prescribed, at least in part due to its potential to cause agranulocytosis …

Background Clozapine is an atypical antipsychotic and the gold standard for treatment-
refractory schizophrenia, that is, for patients in whom at least two traditional antipsychotics …

Decades of research have produced extensive evidence of the contribution of genetic
factors to the efficacy and toxicity of antipsychotics. Numerous genetic variants in genes …

The findings to date are promising and provide us a better understanding of the
development of side effects and response to antipsychotics. However, more comprehensive …

Clozapine is an efficacious atypical antipsychotic for treatment-refractory schizophrenia.
Clinical response and appearance of adverse events vary among individual patients …

Background Genetic polymorphisms are known to influence outcomes with phenytoin yet
effects in the Middle East and North Africa region are poorly understood. Objectives The …

Clozapine pharmacogenomics: a review of efficacy, pharmacoki... : Current Opinion in Psychiatry
Clozapine pharmacogenomics: a review of efficacy, pharmacokinetics, and agranulocytosis …

Clozapine is one of the most effective atypical antipsychotic drugs prescribed to patients with
treatment-resistant schizophrenia. Approximately 1% of patients experience potential life …

Introduction: Pharmacogenetic testing may assist in identifying an individual's risk of
developing a mental illness as well as predict an individual's response to treatment. The …