Efficacy and safety of olanzapine for the prevention of chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis

J Yoodee, U Permsuwan, M Nimworapan - Critical reviews in oncology …, 2017 - Elsevier
Background Olanzapine is an anti-psychotic drug that has been used for preventing and
treating Chemotherapy-Induced Nausea and Vomiting (CINV). This study aimed to …

Efficacy of olanzapine for the prophylaxis of chemotherapy‐induced nausea and vomiting: a meta‐analysis

T Yang, Q Liu, M Lu, L Ma, Y Zhou… - British Journal of Clinical …, 2017 - Wiley Online Library
Aim The aim of the present study was to evaluate the efficacy of olanzapine for the
prevention of chemotherapy‐induced nausea and vomiting (CINV). Methods The literature …

[HTML][HTML] Randomized, placebo-controlled, phase III trial of fosaprepitant, ondansetron, dexamethasone (FOND) versus FOND plus olanzapine (FOND-O) for the …

AB Clemmons, J Orr, B Andrick, A Gandhi… - Biology of Blood and …, 2018 - Elsevier
Evidence supports olanzapine for prophylaxis of chemotherapy-induced nausea/vomiting
(CINV) for highly emetogenic chemotherapy; however, most studies focus on solid …

Olanzapine, an atypical antipsychotic, inhibits survivin expression and sensitizes cancer cells to chemotherapeutic agents

T Sanomachi, S Suzuki, K Kuramoto… - Anticancer …, 2017 - ar.iiarjournals.org
Background/Aim: Olanzapine, an atypical antipsychotic, is now increasingly used as an off-
label indication for the management of cancer patients with chemotherapy-induced nausea …

The use of olanzapine as an antiemetic in palliative medicine: a systematic review of the literature

G Saudemont, C Prod'Homme, A Da Silva, S Villet… - BMC Palliative Care, 2020 - Springer
Background Olanzapine is an atypical antipsychotic that has affinity for many central
nervous system receptors. Its efficacy is supported by several studies in the prevention and …

The efficacy and safety of the addition of olanzapine to ondansetron and dexamethasone for prevention of chemotherapy-induced nausea and vomiting in patients …

V Vimolchalao, S Sakdejayont… - International Journal of …, 2020 - Springer
Objective To evaluate the efficacy and safety of the addition of olanzapine to ondansetron
and dexamethasone for chemotherapy-induced nausea vomiting (CINV) prevention in …

Ghrelin fibers from lateral hypothalamus project to nucleus tractus solitaries and are involved in gastric motility regulation in cisplatin-treated rats

Y Gong, Y Liu, F Liu, S Wang, H Jin, F Guo, L Xu - Brain Research, 2017 - Elsevier
Ghrelin can alleviate cancer chemotherapy-induced dyspepsia in rodents, though the neural
mechanisms involved are not known. Therefore, ghrelin projections from the lateral …

Olanzapine for the prevention of postoperative nausea and vomiting after gynecologic laparoscopic surgery: a randomized controlled trial

N Chen, S Ji, J Liu, L Wang, F Chen… - … Advances in Drug …, 2024 - journals.sagepub.com
Purpose: This study was designed to investigate the prophylactic effect of oral olanzapine in
postoperative nausea and vomiting after gynecologic laparoscopic surgery. Methods: ASA I …

Pharmacokinetics and bioequivalence of 2 olanzapine orally disintegrating tablet products in healthy Chinese Subjects under fed and fasting conditions

L Fan, L Zhang, H Zheng, J Cheng… - Clinical …, 2020 - Wiley Online Library
To assess the bioequivalence of two 5‐mg olanzapine orally disintegrating tablet (ODT)
products, 2 randomized, open‐label, single‐dose, 2‐way crossover studies were carried out …

Should olanzapine be advocated over conventional anti-emetics for the prevention of chemotherapy-induced nausea and vomiting? An updated meta-analysis of …

EI Bahbah, AR Abdalla, K Abdelshafy… - Current Enzyme …, 2019 - benthamdirect.com
Objective: The aim of this study is to synthesize the evidence about the efficacy of
Olanzapine for the prevention of CINV. Methods: A computer literature search of PubMed …