[HTML][HTML] The insecticide deltamethrin enhances sodium channel slow inactivation of human Nav1. 9, Nav1. 8 and Nav1. 7

SN Bothe, A Lampert - Toxicology and applied pharmacology, 2021 - Elsevier
The insecticide deltamethrin of the pyrethroid class mainly targets voltage-gated sodium
channels (Navs). Deltamethrin prolongs the opening of Navs by slowing down fast …

CKIP‐1 mediates CK2 translocation to regulate Nav1. 5 and Kir2. 1 channel complexes in cardiomyocytes

X Li, Y Zhao, M Xue, H Hu, J Yin… - … of Biochemical and …, 2024 - Wiley Online Library
Sodium and potassium channels, especially Nav1. 5 and Kir2. 1, play key roles in the
formation of action potentials in cardiomyocytes. These channels interact with, and are …

Mechanism underlying hooked resurgent-like tail currents induced by an insecticide in human cardiac Nav1. 5

S Thull, C Neacsu, AO O'Reilly, S Bothe… - Toxicology and applied …, 2020 - Elsevier
Voltage-gated sodium channels are responsible not only for the fast upstroke of the action
potential, but they also modify cellular excitability via persistent and resurgent currents …

[PDF][PDF] Pharmacological modification of sodium channel Nav1. 9 activity

S Steup - 2022 - publications.rwth-aachen.de
Voltage-gated sodium channels (Navs) generate the sodium current that is responsible for
the rapid upstroke of the action potential. Therefore, they are a very important component of …