Autoimmune diseases are usually complex and multifactorial, characterized by aberrant
production of autoreactive immune cells and/or autoantibodies against healthy cells and …

Immune-mediated destruction of haematopoietic stem/progenitor cells (HSPCs) plays a
central role in the pathophysiology of acquired aplastic anaemia (aAA). Dysregulated CD8+ …

Prediction of breast cancer response to Neoadjuvant Chemotherapy (NACT) is an urgent
need to promptly direct non-responder patients to alternative therapies. Infiltrating T …

Idiopathic acquired aplastic anemia (aAA) is a rare, life-threatening bone marrow failure
syndrome characterized by cytopenias and a hypocellular bone marrow. Aplastic anemia …

Autophagy is a biological phenomenon whereby components of cells can self-degrade
using autophagosomes. During this process, cells can clear dysfunctional organelles or …

The objective of this study was to predict the value of lymphocyte subsets in cancer
progression. Peripheral blood was obtained from 327 untreated patients with cancer and …

Objectives: In many pediatric acute liver failure (PALF) cases, a diagnosis is not identified,
and the etiology is indeterminate (IND-PALF). Our pilot study found dense CD8 T-cell …

Objective The prognosis of patients with advanced cancers of the upper gastrointestinal
(UGI) tract is poor. Systemic chemotherapy forms the basis for their treatment, with limited …

Aplastic anemia (AA), a rare but potentially life-threatening disease, is a paradigm of bone
marrow failure syndromes characterized by pancytopenia in the peripheral blood and …

Introduction: The past decade or longer has witnessed an acceleration in our understanding
of previously developed immune system and clonal evolution mechanisms, and the genesis …