Single-Cell RNA Sequencing in Organ and Cell Transplantation

R Abedini-Nassab, F Taheri, A Emamgholizadeh… - Biosensors, 2024 - mdpi.com
Single-cell RNA sequencing is a high-throughput novel method that provides transcriptional
profiling of individual cells within biological samples. This method typically uses …

Single cell RNA-sequencing delineates CD8+ tissue resident memory T cells maintaining rejection in liver transplantation

X Li, S Li, Y Wang, X Zhou, F Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Rationale: Understanding the immune mechanisms associated with liver transplantation
(LT), particularly the involvement of tissue-resident memory T cells (TRMs), represents a …

Immune landscape of the kidney allograft in response to rejection

HK Ahuja, S Azim, D Maluf, VR Mas - Clinical Science, 2023 - portlandpress.com
Preventing kidney graft dysfunction and rejection is a critical step in addressing the
nationwide organ shortage and improving patient outcomes. While kidney transplants (KT) …

Single Cell Sequencing and Spatial Transcriptomics in Kidney Transplantation

RS Paul, C Atkinson, AF Malone - Current Transplantation Reports, 2024 - Springer
Abstract Purpose of Review Progress in biology and medicine relies on technological
advances. The ability to examine gene expression from single cells in tissues with complex …

Demystifying tolerance

KA Newell - American Journal of Transplantation, 2023 - amjtransplant.org
Although tolerance to transplanted organs has fascinated clinicians and scientists for
decades, it is only recently that inducing tolerance in selected clinical settings has been …