Cancer and the microbiome—influence of the commensal microbiota on cancer, immune responses, and immunotherapy

V Matson, CS Chervin, TF Gajewski - Gastroenterology, 2021 - Elsevier
The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

The concept of an ideal antibiotic: implications for drug design

M Gajdács - Molecules, 2019 - mdpi.com
The emergence and spread of antibiotic-resistant pathogens is a major public health issue,
which requires global action of an intersectoral nature. Multidrug-resistant (MDR) pathogens …

Bacterial membranes: structure, domains, and function

H Strahl, J Errington - Annual review of microbiology, 2017 - annualreviews.org
The bacterial cytoplasmic membrane is composed of roughly equal proportions of lipids and
proteins. The main lipid components are phospholipids, which vary in acyl chain length …

The role of the tumor microbiome in tumor development and its treatment

Y Chen, FH Wu, PQ Wu, HY Xing, T Ma - Frontiers in Immunology, 2022 - frontiersin.org
Commensal bacteria and other microorganisms that reside in the human body are closely
associated with the development and treatment of cancers. Recently, tumor microbiome …

L-form conversion in Gram-positive bacteria enables escape from phage infection

JC Wohlfarth, M Feldmüller, A Schneller, S Kilcher… - Nature …, 2023 - nature.com
At the end of a lytic bacteriophage replication cycle in Gram-positive bacteria, peptidoglycan-
degrading endolysins that cause explosive cell lysis of the host can also attack non-infected …

Sepsis: mechanisms of bacterial injury to the patient

H Minasyan - Scandinavian journal of trauma, resuscitation and …, 2019 - Springer
In bacteremia the majority of bacterial species are killed by oxidation on the surface of
erythrocytes and digested by local phagocytes in the liver and the spleen. Sepsis-causing …

Rhizophagy cycle: an oxidative process in plants for nutrient extraction from symbiotic microbes

JF White, KL Kingsley, SK Verma, KP Kowalski - Microorganisms, 2018 - mdpi.com
In this paper, we describe a mechanism for the transfer of nutrients from symbiotic microbes
(bacteria and fungi) to host plant roots that we term the 'rhizophagy cycle.'In the rhizophagy …

Possible role of L-form switching in recurrent urinary tract infection

KM Mickiewicz, Y Kawai, L Drage, MC Gomes… - Nature …, 2019 - nature.com
Recurrent urinary tract infection (rUTI) is a major medical problem, especially in the elderly
and infirm, but the nature of the reservoir of organisms responsible for survival and …

Blood microbiome profile in CKD: a pilot study

NB Shah, AS Allegretti, SU Nigwekar… - Clinical Journal of the …, 2019 - journals.lww.com
Results There were 22 operational taxonomic units significantly different between the two
groups. 16S metagenomic sequencing revealed a significant reduction in α diversity (Chao1 …

[HTML][HTML] Lysozyme counteracts β-lactam antibiotics by promoting the emergence of L-form bacteria

Y Kawai, K Mickiewicz, J Errington - Cell, 2018 - cell.com
Summary β-lactam antibiotics inhibit bacterial cell wall assembly and, under classical
microbiological culture conditions that are generally hypotonic, induce explosive cell death …