Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

Introduction Biphasic release, as a special drug-modified release profile that combines
immediate and sustained release, allows fast therapeutic action and retains blood drug …

Since injection administration for diabetes is invasive, it is important to develop an effective
transdermal method for insulin. However, transdermal delivery remains challenging owing to …

The present study deals with the development of transferosomal gel containing insulin by
reverse phase evaporation method for painless insulin delivery for use in the treatment of …

Attempts at replicating physiological insulin secretion, as a means of restoring the normal
metabolic milieu and thereby minimizing the risk of diabetic complications, has become an …

Purpose To assess the feasibility of transdermal macromolecule delivery using novel laser-
engineered dissolving microneedles (MNs) prepared from aqueous blends of 20% w/w poly …

Insulin is used for the treatment of diabetes mellitus, which is characterized by
hyperglycemia. Subcutaneous injections are the standard mode of delivery for insulin …

The use of the transdermal delivery system has recently gained ample recognition due to the
ability to deliver drug molecules across the skin membrane, serving as an alternative to …

The year 2021 marks the 100th anniversary of the momentous discovery of insulin. Through
years of research and discovery, insulin has evolved from poorly defined crude extracts of …

Purpose In previous studies, ultrasound mediated transdermal drug delivery has shown a
promising potential as a method for noninvasive drug administration. For prospective future …