Purpose The role of the microenvironment during the initiation and progression of
carcinogenesis is now realized to be of critical importance, both for enhanced understanding …

“Secretome” is referred to as the rich, complex set of molecules secreted from living cells. In
a less strict definition frequently followed in “secretome” studies, the term also includes …

Infections that result in natural or manmade spread of lethal biological agents are a concern
and require national and focused preparedness. In this manuscript, as part of an early …

The secretome, or secretomics, has recently emerged as a new term to describe the global
study of proteins that are secreted by a cell, tissue or organism at any given time or under …

In the strictest sense, the cell secretome (conditioned media) refers to the collection of
proteins that contain a signal peptide and are processed via the endoplasmic reticulum and …

Biomarkers are pivotal for cancer detection, diagnosis, prognosis and therapeutic
monitoring. However, currently available cancer biomarkers have the disadvantage of …

The analysis of secreted proteins represents a challenge for current proteomics techniques.
Proteins are usually secreted at low concentrations in the culture media, which makes their …

A major but hitherto overseen component of the blood/plasma secretome is that of
extracellular vesicles (EVs) which are shed from all blood cell types. These EVs are made …

The cancer cell secretome may contain many potentially useful biomarkers. We therefore
sought to identify proteins in the conditioned media of colorectal carcinoma (CRC) cell lines …

Purpose: The purpose of this study was to identify proteins that are potentially involved in the
tumor invasion of bladder cancer. Experimental Design: We searched for the candidate …