The magic of bicelles lights up membrane protein structure

UHN Dürr, M Gildenberg, A Ramamoorthy - Chemical reviews, 2012 - ACS Publications
Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

Solid-state NMR of membrane proteins in lipid bilayers: to spin or not to spin?

T Gopinath, D Weber, S Wang, E Larsen… - Accounts of Chemical …, 2021 - ACS Publications
Conspectus Membrane proteins mediate a plethora of cellular functions and represent
important targets for drug development. Unlike soluble proteins, membrane proteins require …

Sensitivity-enhanced multidimensional solid-state NMR spectroscopy by optimal-control-based transverse mixing sequences

J Blahut, MJ Brandl, T Pradhan, B Reif… - Journal of the …, 2022 - ACS Publications
Recently, proton-detected magic-angle spinning (MAS) solid-state nuclear magnetic
resonance (NMR) spectroscopy has become an attractive tool to study the structure and …

Five decades of homonuclear dipolar decoupling in solid-state NMR: Status and outlook

KR Mote, V Agarwal, PK Madhu - Progress in nuclear magnetic resonance …, 2016 - Elsevier
It has been slightly more than fifty years since the first homonuclear spin decoupling
scheme, Lee-Goldburg decoupling, was proposed for removing homonuclear dipolar …

[HTML][HTML] Dual Acquisition Magic Angle Spinning (DUMAS) Solid-State NMR: A New Approach to Simultaneous Acquisition of Multidimensional Spectra of …

T Gopinath, G Veglia - Angewandte Chemie (International ed. in …, 2012 - ncbi.nlm.nih.gov
Magic angle spinning solid-state NMR (MAS ssNMR) spectroscopy is a powerful method for
atomic-resolution structure determination of biomacromolecules that are recalcitrant to …

Activity Quenching of H2O by Donor Interaction for Lithium-Based Batteries

Z Guo, H Yang, Y Yan, P Tang, T Wang, N Piao… - ACS Energy …, 2024 - ACS Publications
In lithium-ion and lithium metal batteries, inevitable H2O molecules limit the electrochemical
performance. Rather than confining or removing H2O molecules, it is more efficient to …

Simplified Preservation of Equivalent Pathways Spectroscopy

E Nimerovsky, AC Varkey, M Kim, S Becker… - JACS Au, 2023 - ACS Publications
Inspired by the recently proposed transverse mixing optimal control pulses (TROP)
approach for improving signal in multidimensional magic-angle spinning (MAS) NMR …

On the role of NMR spectroscopy for characterization of antimicrobial peptides

F Porcelli, A Ramamoorthy, G Barany… - … : Folding, Association, and …, 2013 - Springer
Antimicrobial peptides (AMPs) provide a primordial source of immunity, conferring upon
eukaryotic cells resistance against bacteria, protozoa, and viruses. Despite a few examples …

3D DUMAS: simultaneous acquisition of three-dimensional magic angle spinning solid-state NMR experiments of proteins

T Gopinath, G Veglia - Journal of magnetic resonance, 2012 - Elsevier
Using the DUMAS (Dual acquisition Magic Angle Spinning) solid-state NMR approach, we
created new pulse schemes that enable the simultaneous acquisition of three dimensional …

Orphan spin operators enable the acquisition of multiple 2D and 3D magic angle spinning solid-state NMR spectra

T Gopinath, G Veglia - The Journal of chemical physics, 2013 - pubs.aip.org
We propose a general method that enables the acquisition of multiple 2D and 3D solid-state
NMR spectra for U-13 C, 15 N-labeled proteins. This method, called MEIOSIS (Multiple …