A comparison of the innate and adaptive immune systems in cartilaginous fish, ray-finned fish, and lobe-finned fish

NC Smith, ML Rise, SL Christian - Frontiers in immunology, 2019 - frontiersin.org
The immune system is composed of two subsystems—the innate immune system and the
adaptive immune system. The innate immune system is the first to respond to pathogens and …

The cytokine networks of adaptive immunity in fish

T Wang, CJ Secombes - Fish & shellfish immunology, 2013 - Elsevier
Cytokines, produced at the site of entry of a pathogen, drive inflammatory signals that
regulate the capacity of resident and newly arrived phagocytes to destroy the invading …

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

RA Drummond, M Swamydas, V Oikonomou… - Nature …, 2019 - nature.com
The C-type lectin receptor–Syk (spleen tyrosine kinase) adaptor CARD9 facilitates protective
antifungal immunity within the central nervous system (CNS), as human deficiency in …

Yersinia ruckeri, the causative agent of enteric redmouth disease in fish

G Kumar, S Menanteau-Ledouble, M Saleh… - Veterinary …, 2015 - Springer
Enteric redmouth disease (ERM) is a serious septicemic bacterial disease of salmonid fish
species. It is caused by Yersinia ruckeri, a Gram-negative rod-shaped enterobacterium. It …

Teleost T and NK cell immunity

U Fischer, EO Koppang, T Nakanishi - Fish & shellfish immunology, 2013 - Elsevier
The main function of the immune system is to maintain the organism's homeostasis when
invaded by foreign material or organisms. Prior to successful elimination of the invader it is …

Regulatory roles of cytokines in T and B lymphocytes-mediated immunity in teleost fish

J Cao, H Xu, Y Yu, Z Xu - Developmental & Comparative Immunology, 2023 - Elsevier
Abstract T and B lymphocytes (T and B cells) are immune effector cells that play critical roles
in adaptive immunity and defend against external pathogens in most vertebrates, including …

[HTML][HTML] First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

T Wang, P Johansson, B Abós, A Holt, C Tafalla… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract IL-4 and IL-13 are closely related canonical type-2 cytokines in mammals and have
overlapping bioactivities via shared receptors. They are frequently activated together as part …

Significant alterations of intestinal symbiotic microbiota induced by intraperitoneal vaccination mediate changes in intestinal metabolism of NEW Genetically Improved …

Z Wu, Q Zhang, J Yang, J Zhang, J Fu, C Dang, M Liu… - Microbiome, 2022 - Springer
Background After millions of years of coevolution, symbiotic microbiota has become an
integral part of the host and plays an important role in host immunity, metabolism, and …

Immunomodulatory effects of dietary β-1, 3-glucan from Euglena gracilis in rainbow trout (Oncorhynchus mykiss) immersion vaccinated against Yersinia ruckeri

J Skov, PW Kania, L Holten-Andersen, B Fouz… - Fish & shellfish …, 2012 - Elsevier
Potential immunostimulatory effects of orally administered β-glucan were investigated in
combination with immersion vaccination against enteric redmouth disease caused by …

Cloning and characterization of rainbow trout interleukin-17A/F2 (IL-17A/F2) and IL-17 receptor A: expression during infection and bioactivity of recombinant IL-17A/F2

MM Monte, T Wang, JW Holland, J Zou… - Infection and …, 2013 - Am Soc Microbiol
Lower vertebrates have been found to possess genes that have similar homology to both
interleukin (IL)-17A and IL-17F, which have been termed IL-17A/F. In fish species, several of …