Exploring various techniques for the chemical and biological synthesis of polymeric nanoparticles

T Pulingam, P Foroozandeh, JA Chuah, K Sudesh - Nanomaterials, 2022 - mdpi.com
Nanoparticles (NPs) have remarkable properties for delivering therapeutic drugs to the
body's targeted cells. NPs have shown to be significantly more efficient as drug delivery …

Purification processes of polymeric nanoparticles: How to improve their clinical translation?

SF Tehrani, P Bharadwaj, JL Chain… - Journal of Controlled …, 2023 - Elsevier
Polymeric nanoparticles, as revolutionary nanomedicines, have offered a new class of
diagnostic and therapeutic solutions for a multitude of diseases. With its immense potential …

Advanced biomedical hydrogels: molecular architecture and its impact on medical applications

JT Peters, ME Wechsler… - Regenerative Biomaterials, 2021 - academic.oup.com
Hydrogels are cross-linked polymeric networks swollen in water, physiological aqueous
solutions or biological fluids. They are synthesized by a wide range of polymerization …

Artificial intelligence in nanomedicine

D Ho, P Wang, T Kee - Nanoscale Horizons, 2019 - pubs.rsc.org
The field of nanomedicine has made substantial strides in the areas of therapeutic and
diagnostic development. For example, nanoparticle-modified drug compounds and imaging …

Self-therapeutic nanomaterials: Applications in biology and medicine

J Seaberg, JR Clegg, R Bhattacharya, P Mukherjee - Materials Today, 2023 - Elsevier
Over past decades, nanotechnology has contributed to the biomedical field in areas
including detection, diagnosis, and drug delivery via opto-electronic properties or …

Surface‐bound microgels for separation, sensing, and biomedical applications

CC Cutright, JL Harris, S Ramesh… - Advanced Functional …, 2021 - Wiley Online Library
This study presents a comprehensive survey of microgel‐coated materials and their
functional behavior, describing the complex interplay between the physicochemical and …

Paracellular delivery of protein drugs with smart enteropatho nanoparticles

I Ramirez-Velez, AA Namjoshi, UM Effiong… - ACS …, 2024 - ACS Publications
A general platform for the safe and effective oral delivery of biologics would revolutionize the
administration of protein-based drugs, improving access for patients and lowering the …

Synthetic networks with tunable responsiveness, biodegradation, and molecular recognition for precision medicine applications

JR Clegg, AS Irani, EW Ander, CM Ludolph… - Science …, 2019 - science.org
Formulations and devices for precision medicine applications must be tunable and
multiresponsive to treat heterogeneous patient populations in a calibrated and individual …

Model-based modular hydrogel design

N Richbourg, ME Wechsler… - Nature Reviews …, 2024 - nature.com
Abstract Hydrogels—water-insoluble, three-dimensional networks of polymer chains—are
used as biomaterials in various biomedical and clinical applications. Their modularity and …

Hyperbranched Copolymers of Methacrylic Acid and Lauryl Methacrylate HP (MAA-co-LMA): Synthetic Aspects and Interactions with Biorelevant Compounds

A Balafouti, S Pispas - Pharmaceutics, 2023 - mdpi.com
The synthesis of novel copolymers using one-step reversible addition-fragmentation chain
transfer (RAFT) copolymerization of biocompatible methacrylic acid (MAA), lauryl …