Plant-based natural products and extracts: Potential source to develop new antiviral drug candidates

E Thomas, LE Stewart, BA Darley, AM Pham, I Esteban… - Molecules, 2021 - mdpi.com
Viral infections are among the most complex medical problems and have been a major
threat to the economy and global health. Several epidemics and pandemics have occurred …

Structure-activity-relationship and mechanistic insights for anti-HIV natural products

R Kaur, P Sharma, GK Gupta, F Ntie-Kang, D Kumar - Molecules, 2020 - mdpi.com
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …

Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review

AI Elshamy, TA Mohamed, AF Essa, AM Abd-El Gawad… - Nutrients, 2019 - mdpi.com
Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are
distributed in Asia, especially in the southeast region, and Thailand. They have been widely …

The HIV-1 Vpr protein: a multifaceted target for therapeutic intervention

ME González - International journal of molecular sciences, 2017 - mdpi.com
The human immunodeficiency virus type 1 (HIV-1) Vpr protein is an attractive target for
antiretroviral drug development. The conservation both of the structure along virus evolution …

Pimarane diterpenes: Natural source, stereochemical configuration, and biological activity

P Reveglia, A Cimmino, M Masi, P Nocera, N Berova… - Chirality, 2018 - Wiley Online Library
Plants and fungi are seemingly inexhaustible sources of interesting natural products with
remarkable structural and biological diversity. One of the most important groups is the …

Viral protein R inhibitors from Swertia chirata of Myanmar

SY Woo, NN Win, WMN Oo, H Ngwe, T Ito, I Abe… - Journal of bioscience …, 2019 - Elsevier
Viral protein R (Vpr) is a small, basic accessory protein (14 kDa) that is well conserved in
Human immunodeficiency virus-1 (HIV-1), HIV-2, and simian immunodeficiency virus (SIV) …

Traditional medicinal plants used by the Mon people in Myanmar

YMM Kyaw, Y Bi, TN Oo, X Yang - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Myanmar's Mon people largely depend on a
traditional medical system for health care, however, information about their medical plants is …

[PDF][PDF] Antiviral properties of diterpenes and their derivatives

OI Yarovaya, SS Laev, NF Salakhutdinov - Russ. Chem. Rev, 2023 - researchgate.net
Virus is a noncellular infectious agent that reproduces only inside living cells. Viruses infect
various types of organisms such as bacteria, plants, animals and humans. The officially …

Bis-iridoid and iridoid glycosides: Viral protein R inhibitors from Picrorhiza kurroa collected in Myanmar

NN Win, T Kodama, KZW Lae, YY Win, H Ngwe, I Abe… - Fitoterapia, 2019 - Elsevier
Four new bis-iridoid glycosides, saungmaygaosides AD (1–4), and six known iridoid
glycosides (5–10) were isolated from the n-butanol extract of the stems of Picrorhiza kurroa …

Kaemgalangol A: Unusual seco-isopimarane diterpenoid from aromatic ginger Kaempferia galanga

N Swapana, T Tominaga, AI Elshamy, MAA Ibrahim… - Fitoterapia, 2018 - Elsevier
A new unusual seco-isopimarane, kaemgalangol A (1) and 12 usual analogs (2− 13) were
isolated from the rhizomes of Kaempferia galanga (Family: Zingiberaceae). KaemgalangolA …