Hyperbaric oxygen therapy (HBOT) consists of using of pure oxygen at increased pressure
(in general, 2–3 atmospheres) leading to augmented oxygen levels in the blood …

The increasing emergence of multidrug-resistant (MDR) pathogens causes difficult-to-treat
infections with long-term hospitalizations and a high incidence of death, thus representing a …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

HIF is a transcription factor that plays an essential role in the cellular response to low
oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In …

Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial
inflammation, pannus formation, and bone and cartilage damage. It has a high disability …

Neuroinflammation is a common event in degenerative diseases of the central and
peripheral nervous system, triggered by alterations in the immune system or inflammatory …

Abstract T helper (Th) 17 cells, a distinct subset of Th lymphocytes, are known for their
prominent interleukin (IL)-17 production and other pro-inflammatory cytokines. These cells …

The perception of sepsis has shifted over time; however, it remains a leading cause of death
worldwide. Sepsis is now recognized as an imbalance in host cellular functions triggered by …

Enhancement of glycolysis and glutaminolysis are the two most common modalities
associated with metabolic reprogramming in rheumatoid arthritis (RA). This enhancement is …

Inflammatory bowel diseases, with an increasing incidence, pose a significant health
burden. Although there have been significant advances in the treatment of IBD, more …