Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review
WY Fang, L Ravindar, KP Rakesh… - European Journal of …, 2019 - Elsevier
At present more than 250 FDA approved chlorine containing drugs were available in the
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …
market and many pharmaceutically important drug candidates in pre-clinical trials. Thus, it is …
Synthesis of quinoline derivatives as diabetic II inhibitors and molecular docking studies
In searchof the potenttherapeutic agent as an α-glucosidase inhibitor, we have synthesized
twenty-five analogs (1–25) of quinoline-based Schiff bases as an inhibitoragainst α …
twenty-five analogs (1–25) of quinoline-based Schiff bases as an inhibitoragainst α …
Synthesis, biological activities, and molecular docking studies of 2-mercaptobenzimidazole based derivatives
A new series of N-acylhydrazone derivatives of 2-mercaptobenzimidazole (2-MBI) has been
synthesized through S-alkylation with 1-bromotetradecane and N-alkylation with ethyl-2 …
synthesized through S-alkylation with 1-bromotetradecane and N-alkylation with ethyl-2 …
Synthesis of novel quinoline-based thiadiazole, evaluation of their antileishmanial potential and molecular docking studies
New series of quinoline-based thiadiazole analogs (1–20) were synthesized, characterized
by EI-MS, 1 H NMR and 13 C NMR. All synthesized compounds were subjected to their …
by EI-MS, 1 H NMR and 13 C NMR. All synthesized compounds were subjected to their …
Mercaptobenzimidazole-based 1, 3-thaizolidin-4-ones as antidiabetic agents: synthesis, in vitro α-glucosidase inhibition activity, and molecular docking studies
In this research work, we have focused our efforts to synthesize a series of 2-
mercaptobenzimidazole-based 1, 3-thiazolidin-4-ones (5–24) following a multistep reaction …
mercaptobenzimidazole-based 1, 3-thiazolidin-4-ones (5–24) following a multistep reaction …
Synthesis, in vitro evaluation and molecular docking studies of hybrid 4-quinolinyl bearing 1, 3, 4-thiadiazole-2-amine as a new inhibitor of α-amylase and α …
Abstract Synthesized scaffolds (1–19) of 4-quinolinyl based 1, 3, 4-thiadiazole-2-amine were
evaluated in vitro for their α-amylase and α-glucosidase inhibition. All the newly synthesized …
evaluated in vitro for their α-amylase and α-glucosidase inhibition. All the newly synthesized …
Ultrasound-assisted improved synthesis of 5-(benzylthio)-1, 3, 4-thiadiazol-2-amine derivatives: an experimental and computational study
T Erdogan - Journal of the Iranian Chemical Society, 2019 - Springer
The main objects of this study are:(1) to propose alternative efficient methods for the
synthesis of 5-amino-1, 3, 4-thiadiazole-2-thiol and 5-(benzylthio)-1, 3, 4-thiadiazol-2-amine …
synthesis of 5-amino-1, 3, 4-thiadiazole-2-thiol and 5-(benzylthio)-1, 3, 4-thiadiazol-2-amine …
[PDF][PDF] THERMODYNAMICAL ANALYSIS OF GEOTHERMAL POWERED ORGANIC RANKINE CYCLE FOR R-1233ZD, R-600, R-245FA AND R-236FA
MŞ ACAR - PROCEEDINGS BOOK, 2019 - masjournal.co.uk
In this study, the net power outputs, energy and exergy efficiencies of the Organic Rankine
cycle was investigated for different operating parameters and working fluids. The geothermal …
cycle was investigated for different operating parameters and working fluids. The geothermal …