Nuclear factor-kappa B and its role in inflammatory lung disease

KS Alharbi, NK Fuloria, S Fuloria, SB Rahman… - Chemico-biological …, 2021 - Elsevier
Nuclear factor-kappa B, involved in inflammation, host immune response, cell adhesion,
growth signals, cell proliferation, cell differentiation, and apoptosis defense, is a dimeric …

[HTML][HTML] Kaempferol: Paving the path for advanced treatments in aging-related diseases

MS Hussain, ASA Altamimi, M Afzal, WH Almalki… - Experimental …, 2024 - Elsevier
Aging-related diseases (ARDs) are a major global health concern, and the development of
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …

The relationship between previous pulmonary tuberculosis and risk of lung cancer in the future

Y Qin, Y Chen, J Chen, K Xu, F Xu, J Shi - Infectious Agents and Cancer, 2022 - Springer
Various investigations have expanded the views that tuberculosis is an important risk factor
for lung cancer occurrence. Lung cancer originates from chronic inflammation and infection …

Childhood maltreatment and DNA methylation: a systematic review

M Rubens, D Bruenig, JAM Adams, SM Suresh… - Neuroscience & …, 2023 - Elsevier
Child maltreatment (CM) encompasses sexual abuse, physical abuse, emotional abuse,
neglect, and exposure to domestic and family violence. Epigenetic research investigating …

The role of pharmacogenetics in personalizing the antidepressant and anxiolytic therapy

M Radosavljevic, D Svob Strac, J Jancic, J Samardzic - Genes, 2023 - mdpi.com
Pharmacotherapy for neuropsychiatric disorders, such as anxiety and depression, has been
characterized by significant inter-individual variability in drug response and the development …

Introduction to epigenetics

N Singla, R Thapa, R Kulshrestha, AA Bhat… - Targeting epigenetics in …, 2023 - Springer
Epigenetics is the study of inherited variations in gene expression that do not involve
changes to DNA sequences. Over 200 unique cell types in a human adult have a nearly …

Non-coding RNAs (ncRNAs) and multidrug resistance in glioblastoma: Therapeutic challenges and opportunities

GM Subaiea, RU Syed, S Afsar, TMS Alhaidan… - … -Research and Practice, 2024 - Elsevier
Non-coding RNAs (ncRNAs) have been recognized as pivotal regulators of transcriptional
and post-transcriptional gene modulation, exerting a profound influence on a diverse array …

A narrative review on the biology of piezo1 with platelet-rich plasma in cardiac cell regeneration

KS Alharbi, WH Almalki, SI Alzarea, I Kazmi… - Chemico-Biological …, 2022 - Elsevier
Cardiomyocyte regeneration following cardiac damage is challenging to study because of
the inflammatory process, the multiplication of cells in the stroma, and the creation of scar …

Pyroptosis-related non-coding RNAs emerging players in atherosclerosis pathology

WMA Khojali, NE Khalifa, F Alshammari, S Afsar… - … -Research and Practice, 2024 - Elsevier
Globally, atherosclerosis a persistent inflammatory condition of the artery walls continues to
be the primary cause of cardiovascular illness and death. The ncRNAs are important …

Sepsis triggered oxidative stress-inflammatory axis: the pathobiology of reprogramming in the normal sleep–wake cycle

WH Almalki, MM Ghoneim, S Alshehri, SS Imam… - Molecular and Cellular …, 2022 - Springer
In individuals with sepsis-related neurodegenerative illness, sleep and circadian rhythm
disturbance are common. The alteration in genomic expression linked with the immune …