N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Background There is an expanding field of research investigating the benefits of medicines
with multiple mechanisms of action across neurological disorders. N‐acetylcysteine (NAC) …

Mitochondrial function and specifically its implication in cellular redox/oxidative balance is
fundamental in controlling the life and death of cells, and has been implicated in a wide …

Free radicals and inflammatory mediators are involved in transient focal cerebral ischemia
(FCI). Preadministration of N‐acetylcysteine (NAC) has been found to attenuate the cerebral …

Background Mild traumatic brain injury (mTBI) secondary to blast exposure is the most
common battlefield injury in Southwest Asia. There has been little prospective work in the …

Ischemic cerebrovascular disease (stroke) is one of the leading causes of death and long-
time disability. Ischemia/reperfusion to any organ triggers a complex series of biochemical …

Objective Maternal inflammation/infection alone or in combination with birth asphyxia
increases the risk for perinatal brain injury. Free radicals are implicated as major mediators …

In this study, using two different injury models in two different species, we found that early
post-injury treatment with N-Acetyl Cysteine (NAC) reversed the behavioral deficits …

Spinal cord injury (SCI) is a major health problem and is associated with a diversity of
neurological symptoms. Pathophysiologically, dysfunction after SCI results from the …