RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

The human body harbors a diverse ecosystem of microorganisms, including bacteria,
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Neurological disorders are a common feature in patients who recover from severe acute
pneumonia. However, the underlying mechanisms remain poorly understood. Here, we …

Respiratory infections are common in infants and young children. However, the immune
system develops and matures as the child grows, thus the effects of infection during this time …

Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of
people with cystic fibrosis and is one of the most common causes of infectious-disease …

Lung cancer and chronic obstructive pulmonary disease (COPD) often co-occur, and
individuals with COPD are at a higher risk of developing lung cancer. While the underlying …

The human microbiome is a complex and dynamic system that plays important roles in
human health and disease. However, there remain limitations and theoretical gaps in our …

Most eukaryotes require oxygen for their survival and, with increasing multicellular
complexity, oxygen availability and delivery rates vary across the tissues of complex …

The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …