As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …

Albumin has shown remarkable promise as a natural drug carrier by improving
pharmacokinetic (PK) profiles of anticancer drugs for tumor-targeted delivery. The …

Rationale: Cancer immunotherapy combining immune checkpoint blockade (ICB) with
chemotherapeutic drugs has provided significant clinical advances. However, such …

Cathepsin B (CTSB), a lysosomal cysteine protease, plays an important role in human
physiology and pathology. CTSB is associated with various human diseases, and its …

Over the past few decades, the enhanced permeability and retention (EPR) effect of
nanomedicine has been a crucial phenomenon in targeted cancer therapy. Specifically …

Monospecific antibodies have been utilised increasingly for anti-cancer drug targeting owing
to their ability to minimise off-target toxicity by binding specifically to a tumour epitope, hence …

Ovarian cancer is a highly lethal disease that affects women. Early diagnosis and treatment
of women with early-stage disease improve the probability of survival. Unfortunately, the …

Several abdominal-located cancers develop metastasis within the peritoneum, what is
called peritoneal carcinomatosis (PC), constituting a clinical challenge in their therapeutical …

Background: Doxorubicin (DOX) is an effective broad-spectrum antitumor drug, but its
clinical application is limited due to the side effects of cardiac damage. Astragaloside IV (AS …

Ovarian cancer cells usually spread in the peritoneal region, and if chemotherapeutic drugs
can be given in these regions with proximity, then the anticancer property of the …