Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …

Background The most manifest long-term consequences of radiation therapy in the head
and neck cancer patient are salivary gland hypofunction and a sensation of oral dryness …

Abstract Purpose To develop a European White Paper document on oropharyngeal
dysphagia (OD) in head and neck cancer (HNC). There are wide variations in the …

PURPOSE To provide evidence-based recommendations for prevention and management
of salivary gland hypofunction and xerostomia induced by nonsurgical cancer therapies …

Survivors of head and neck cancer can experience long-term consequences of the cancer
and subsequent treatments even after the cancer has resolved. Increasingly clinicians are …

Purpose of this review of medical literature is to present the immediate side effects of
radiation therapy for head and neck cancer and their treatment. The likelihood and severity …

Xerostomia and hyposalivation are highly prevalent conditions in old age, particularly
among multimorbid elders, and are often attributed to the use of multiple medications. These …

The main role of salivary glands (SG) is the production and secretion of saliva, in which
aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane …

Salivary glands (SGs) play a vital role in maintaining oral health through the production and
release of saliva. Injury to SGs can lead to gland hypofunction and a decrease in saliva …

Management of salivary gland hypofunction caused by irradiation (IR) therapy for head and
neck cancer remains lack of effective treatments. Salivary glands, especially the parotid …