Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Dinuclear metal complexes: multifunctional properties and applications

G Li, D Zhu, X Wang, Z Su, MR Bryce - Chemical Society Reviews, 2020 - pubs.rsc.org
The development of metal complexes for optoelectronic applications is a fertile area of
research. In contrast to the rigorous development of mononuclear metal complexes …

Anticancer metal-N-heterocyclic carbene complexes of gold, platinum and palladium

T Zou, CN Lok, PK Wan, ZF Zhang, SK Fung… - Current opinion in …, 2018 - Elsevier
Highlights•Metal-NHC complexes have their metal centers stabilized under physiological
conditions and can exhibit anticancer activity.•Metal-NHC complexes having new …

Synthesis of hemilabile cyclic (alkyl)(amino) carbenes (CAACs) and applications in organometallic chemistry

J Chu, D Munz, R Jazzar, M Melaimi… - Journal of the American …, 2016 - ACS Publications
A versatile methodology, involving readily available starting materials, allows for the
synthesis of stable hemilabile bidentate cyclic (alkyl)(amino) carbenes (CAACs) featuring …

Advances in alkynyl gold complexes for use as potential anticancer agents

Z Yang, G Jiang, Z Xu, S Zhao, W Liu - Coordination Chemistry Reviews, 2020 - Elsevier
Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …

Deep red PhOLED from dimeric salophen Platinum (II) complexes

J Zhang, L Wang, A Zhong, G Huang, F Wu, D Li… - Dyes and …, 2019 - Elsevier
Abstract The condensation of 3, 3′-diaminobenzidine with different substituted
salicylaldehyde afforded three dimeric salophen ligands H 4 L 1-H 4 L 3. Subsequently, their …

Interplay between cellular metabolism and the DNA damage response in cancer

A Moretton, JI Loizou - Cancers, 2020 - mdpi.com
Metabolism is a fundamental cellular process that can become harmful for cells by leading to
DNA damage, for instance by an increase in oxidative stress or through the generation of …

Metals in cancer research: Beyond platinum metallodrugs

A Casini, A Pöthig - ACS Central Science, 2024 - ACS Publications
The discovery of the medicinal properties of platinum complexes has fueled the design and
synthesis of new anticancer metallodrugs endowed with unique modes of action (MoA) …