New pathological and clinical insights in endometrial cancer in view of the updated ESGO/ESTRO/ESP guidelines

A Santoro, G Angelico, A Travaglino, F Inzani… - Cancers, 2021 - mdpi.com
Simple Summary Histopathological classification of endometrial carcinoma has evidenced
two main groups with different biological behavior: low-grade (G1–G2) and high-grade (G3) …

Endometrial carcinoma: molecular subtypes, precursors and the role of pathology in early diagnosis

J Huvila, J Pors, EF Thompson… - The Journal of …, 2021 - Wiley Online Library
Endometrial carcinoma (EC) is classified into a wide range of morphological variants; this list
has expanded over the past decade with the inclusion of mesonephric‐like and …

TCGA molecular prognostic groups of endometrial carcinoma: current knowledge and future perspectives

D Arciuolo, A Travaglino, A Raffone… - International journal of …, 2022 - mdpi.com
The four TCGA-based molecular prognostic groups of endometrial carcinoma (EC), ie, POLE-
mutant, mismatch repair (MMR)-deficient, p53-abnormal, and “no specific molecular …

TCGA molecular groups of endometrial cancer: pooled data about prognosis

A Raffone, A Travaglino, M Mascolo, L Carbone… - Gynecologic …, 2019 - Elsevier
Abstract Background After The Cancer Genome Atlas (TCGA) findings, four novel prognostic
groups may direct the management of endometrial cancer (EC): POLE-mutated/ultramutated …

Current approaches to the management of patients with endometrial cancer

E Kalampokas, G Giannis, T Kalampokas… - Cancers, 2022 - mdpi.com
Simple Summary New data, the development of new methods of treatment and management
and the rising incidence of endometrial cancer require constant reviewing, in order to inform …

[HTML][HTML] Genomic landscape of endometrial carcinomas of no specific molecular profile

A Momeni-Boroujeni, B Nguyen, CM Vanderbilt… - Modern Pathology, 2022 - Elsevier
Endometrial carcinomas (ECs) classified by The Cancer Genome Atlas (TCGA) as copy
number-low (also referred to as “no specific molecular profile”[NSMP]) have a prognosis …

Predicting endometrial cancer subtypes and molecular features from histopathology images using multi-resolution deep learning models

R Hong, W Liu, D DeLair, N Razavian, D Fenyö - Cell Reports Medicine, 2021 - cell.com
The determination of endometrial carcinoma histological subtypes, molecular subtypes, and
mutation status is critical for the diagnostic process, and directly affects patients' prognosis …

TCGA molecular subgroups in endometrial undifferentiated/dedifferentiated carcinoma

A Travaglino, A Raffone, M Mascolo, M Guida… - Pathology & Oncology …, 2020 - Springer
We aimed to classify undifferentiated/dedifferentiated carcinoma (UDC/DDC) according to
the four TCGA molecular subgroups of endometrial cancer: microsatellite …

TCGA classification of endometrial cancer: the place of carcinosarcoma

A Travaglino, A Raffone, A Gencarelli, A Mollo… - Pathology & Oncology …, 2020 - Springer
Abstract In 2013, The Cancer Genome Atlas (TCGA) Research Network found four novel
prognostic subgroups of endometrial carcinoma: POLE/ultramutated (POLE), microsatellite …

POLE, MMR, and MSI testing in endometrial cancer: proceedings of the ISGyP companion society session at the USCAP 2020 annual meeting

L Casey, N Singh - International Journal of Gynecological …, 2021 - journals.lww.com
Subclassification of endometrial carcinoma (EC) based on morphologic features alone has
been shown to have suboptimal reproducibility, both in regard to biopsy versus …