Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …

NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

The enterococci, which are among the leading causes of multidrug-resistant (MDR) hospital
infection, are notable for their environmental ruggedness, which extends to intrinsic …

Antibiotic resistance and the ability to form biofilms of Enterococcus faecalis have
compromised the choice of therapeutic options, which triggered the search for new …

Enterococcus faecalis and Enterococcus faecium are Gram-positive commensal gut bacteria
that can also cause fatal infections. To study clinically relevant multi-drug resistant E …

Gram-positive bacteria surround themselves with a multilayered macromolecular cell wall
that is essential to cell survival and serves as a major target for antibiotics. The cell wall of …

Bacteria surround themselves with cell walls to maintain cell rigidity and protect against
environmental insults. Here we review chemical and biochemical techniques employed to …

Daptomycin is a cyclic lipodepsipeptide antibiotic reserved for the treatment of serious
infections by multidrug-resistant Gram-positive pathogens. Its mode of action is considered …

Peptidoglycan (PG) is a ubiquitous structural polysaccharide of the bacterial cell wall,
essential in preserving cell integrity by withstanding turgor pressure. Any change that affects …