Melatonin, along with its metabolites, have long been known to significantly reduce the
oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a …

Melatonin, as a neuroendocrine hormone, is produced primarily by the pineal gland.
Melatonin, a pleotropic molecule, acts as a free radical scavenger, antioxidant, and regulator …

The objective of this article is to review the basis supporting the usefulness of melatonin as
an adjuvant therapy for breast cancer (BC) prevention in several groups of individuals at …

At present, glyphosate (GLP) is the most produced and used herbicide in the world. With the
large-scale use of glyphosate-based herbicides (GBHs), their toxic effects on animals and …

High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via
oxidative stress and inflammation. The aim of this study is to demonstrate the protective …

Purpose Myocardial ischemia–reperfusion (I/R) injury is associated with systemic oxidative
stress, cardiac mitochondrial homeostasis, and cardiomyocyte apoptosis. Metformin has …

Melatonin (MT) influences lipid metabolism in animals; however, the mechanistic effect of
melatonin on liver fat and abdominal adipose deposition requires further clarity. In order to …

Melatonin is a neurohormone synthesized from dietary tryptophan in various organs,
including the pineal gland and the retina. In the pineal gland, melatonin is produced at night …

Imbalanced glucose tolerance and insulin resistance remain important as high cancer risk
factors. Metformin administration to diabetic patients may be associated with a reduced risk …

Purpose Obesity-induced insulin resistant is associated with cardiovascular diseases via
impairing cardiac mitochondria. Recently, d-allulose could protect β-islets and improve …