Pax genes play key roles in the formation of tissues and organs during embryogenesis.
Pax3 and Pax7 mark myogenic progenitor cells and regulate their behavior and their entry …

Introduction• Pax proteins in muscle formation• Pax7/MRF cross‐regulation and the control
of satellite cell fate• Transcriptional and non‐transcriptional Pax7 functions in myogenic …

Cross-talk between the Hippo and Wnt pathways has been implicated recently in breast
cancer development, but key intersections have yet to be fully defined. Here we report that …

WW domain-binding protein 2 (WBP2) has been demonstrated as oncogenic in breast
cancer. Many studies have revealed the WBP2 gene as a high-risk gene for leukoariaosis …

Pax8 and TTF-1 are transcription factors involved in the morphogenesis of the thyroid gland
and in the transcriptional regulation of thyroid-specific genes. Both proteins are expressed in …

WW domain-binding protein 2 (WBP2) is an emerging oncoprotein. Over the past decade,
WBP2 surfaced as a key node connecting key signaling pathways associated with ER/PR …

Background Surgery combined with new adjuvant chemotherapy is the primary treatment for
early stage invasive and advanced stage breast cancer. Growing evidence indicates that …

The WW domain is composed of 38 to 40 semi-conserved amino acids shared with
structural, regulatory, and signaling proteins. WW domain-binding protein 2 (WBP2), as a …

Background/Aims: Dysregulated expression of WW domain-binding protein 2 (WBP2) is
associated with poor prognosis in ER+ breast cancer patients. However, its role in triple …

Abstract TAZ (WWTR1), identified as a 14-3-3 binding protein with a PDZ binding motif, is
implicated in mesenchymal stem cell differentiation. TAZ has been shown to be negatively …