Helicobacter pylori infection is a well-established risk factor for the development of gastric
cancer (GC). Understanding the immunopathogenesis underlying this association is crucial …

Helicobacter pylori (H. pylori) is a bacterial pathogen that resides in more than half of the
human population and has co-evolved with humans for more than 58,000 years. This …

Helicobacter pylori (H. pylori) is a human pathogen affecting over 50% of the world
population. This pathogen is usually associated with chronic inflammation of the gastric …

Although millions of people have been infected by Helicobacter pylori (H. pylori), only a
small proportion of infected individuals will develop adverse outcomes, ranging from chronic …

Helicobacter pylori infection is a risk factor for the development of gastric cancer (GC), and
the role of co-infection with viruses, such as Epstein-Barr virus, in carcinogenesis cannot be …

Helicobacter pylori infection induces a chronic gastric inflammation which can lead to gastric
ulcers and cancer. The mucosal immune response to H. pylori is first initiated by the …

Immuno-oncology has rapidly grown in the last thirty years, and immunotherapeutic agents
are now approved to treat many disparate cancers. Immune checkpoint inhibitors (ICIs) are …

Peptic ulcer disease (PUD) is the result of defects in the gastroduodenal mucosa mediated
by an imbalance of mucosal protective and mucosal damaging mechanisms, thus leading to …

Objective. The clinical outcomes of gastric diseases such as chronic gastritis, peptic ulcer,
and gastric cancer have been attributed to the interplay of virulence factors of Helicobacter …

Helicobacter pylori (H. pylori) colonizes the stomach and leads to the secretion of a vast
range of cytokines by infiltrated leukocytes directing immune/inflammatory response against …