Collagen cross-linking: when and how? A review of the state of the art of the technique and new perspectives

L Mastropasqua - Eye and Vision, 2015 - Springer
Since the late 1990s corneal crosslinking (CXL) has been proposed as a new possibility to
stop progression of keratoconus or secondary corneal ectasia, with the promising aim to …

Corneal cross-linking: the science beyond the myths and misconceptions

RS Rubinfeld, C Caruso, C Ostacolo - Cornea, 2019 - journals.lww.com
Purpose: There has been a recent explosion in the variety of techniques used to accomplish
corneal cross-linking (CXL) for the treatment of ectatic corneal diseases. To understand the …

Randomized controlled trial comparing transepithelial corneal cross-linking using iontophoresis with the Dresden protocol in progressive keratoconus

M Lombardo, D Giannini, G Lombardo, S Serrao - Ophthalmology, 2017 - Elsevier
Purpose To compare clinical outcomes of transepithelial corneal cross-linking using
iontophoresis (T-ionto CL) and standard corneal cross-linking (standard CL) for the …

Corneal collagen crosslinking for corneal ectasias: a review

DPS O'Brart - European Journal of Ophthalmology, 2017 - journals.sagepub.com
Purpose To review the published literature on corneal collagen crosslinking (CXL). Methods
Importance has been placed on seminal publications, systemic reviews, meta-analyses, and …

Corneal cross-linking for pediatric keratcoconus review

C Perez-Straziota, RN Gaster, YS Rabinowitz - Cornea, 2018 - journals.lww.com
Purpose: To comprehensively review the available published literature for cross-linking in
the pediatric population. Methods: Review of the literature published in English in PubMed …

Basic principles and current status of transcorneal and transscleral iontophoresis

T Gratieri, V Santer, YN Kalia - Expert opinion on drug delivery, 2017 - Taylor & Francis
Introduction: Iontophoresis is an active non-invasive drug delivery technique that can
increase the transport of charged and neutral molecules into and across biological …

Oxygen diffusion may limit the biomechanical effectiveness of iontophoresis-assisted transepithelial corneal cross-linking

EA Torres-Netto, S Kling, N Hafezi… - Journal of Refractive …, 2018 - journals.healio.com
PURPOSE: To evaluate the impact of varying treatment time on the efficacy of iontophoresis-
assisted transepithelial corneal cross-linking (I-CXL) in ex vivo porcine corneas. METHODS …

Two-year outcomes of a randomized controlled trial of transepithelial corneal crosslinking with iontophoresis for keratoconus

M Lombardo, S Serrao, G Lombardo… - Journal of Cataract & …, 2019 - journals.lww.com
Two-year outcomes of a randomized controlled trial of transe... : Journal of Cataract & Refractive
Surgery Two-year outcomes of a randomized controlled trial of transepithelial corneal …

Interaction of ultraviolet light with the cornea: clinical implications for corneal crosslinking

M Lombardo, G Pucci, R Barberi… - Journal of Cataract & …, 2015 - Elsevier
Understanding ultraviolet (UV) interaction with the human corneal tissue is of interest among
corneal specialists given the widespread application of corneal crosslinking. This article …

Conventional and iontophoresis corneal cross-linking for keratoconus: efficacy and assessment by optical coherence tomography and confocal microscopy

L Jouve, V Borderie, O Sandali, C Temstet, E Basli… - Cornea, 2017 - journals.lww.com
Purpose: To compare the efficacy, safety, and microstructural corneal changes during 2
years after conventional corneal collagen cross-linking (C-CXL) and transepithelial corneal …