Polyploidy has been hypothesized to be both an evolutionary dead-end and a source for
evolutionary innovation and species diversification. Although polyploid organisms …

Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …

Gene duplications have long been recognized as a contributor to the evolution of genes with
new functions. Multiple copies of genes can result from tandem duplication, from …

Major advances in crop yields are needed in the coming decades. However, plant breeding
is currently limited by incremental improvements in quantitative traits that often rely on …

To explore the origins and consequences of tetraploidy in the African clawed frog, we
sequenced the Xenopus laevis genome and compared it to the related diploid X. tropicalis …

Whole exome sequencing has proven to be a powerful tool for understanding the genetic
architecture of human disease. Here we apply it to more than 2,500 simplex families, each …

Different plant species within the grasses were parallel targets of domestication, giving rise
to crops with distinct evolutionary histories and traits. Key traits that distinguish these species …

Sturgeons seem to be frozen in time. The archaic characteristics of this ancient fish lineage
place it in a key phylogenetic position at the base of the~ 30,000 modern teleost fish …

Whole-genome duplication (WGD) is characteristic of almost all fundamental lineages of
land plants. Unfortunately, the timings of WGD events are loosely constrained and …

All natural plant species are evolved from ancient polyploids. Polyloidization plays an
important role in plant genome evolution, species divergence and crop domestication. We …