Ecology, evolution and spillover of coronaviruses from bats

M Ruiz-Aravena, C McKee, A Gamble, T Lunn… - Nature Reviews …, 2022 - nature.com
In the past two decades, three coronaviruses with ancestral origins in bats have emerged
and caused widespread outbreaks in humans, including severe acute respiratory syndrome …

Vaccines to emerging viruses: Nipah and Hendra

M Amaya, CC Broder - Annual review of virology, 2020 - annualreviews.org
Hendra virus (HeV) and Nipah virus (NiV) are bat-borne zoonotic para-myxoviruses
identified in the mid-to late 1990s in outbreaks of severe disease in livestock and people in …

Pathogen spillover driven by rapid changes in bat ecology

P Eby, AJ Peel, A Hoegh, W Madden, JR Giles… - Nature, 2023 - nature.com
During recent decades, pathogens that originated in bats have become an increasing public
health concern. A major challenge is to identify how those pathogens spill over into human …

Individual bat virome analysis reveals co-infection and spillover among bats and virus zoonotic potential

J Wang, Y Pan, L Yang, W Yang, K Lv, C Luo… - Nature …, 2023 - nature.com
Bats are reservoir hosts for many zoonotic viruses. Despite this, relatively little is known
about the diversity and abundance of viruses within individual bats, and hence the …

Land use-induced spillover: a call to action to safeguard environmental, animal, and human health

RK Plowright, JK Reaser, H Locke… - The Lancet Planetary …, 2021 - thelancet.com
The rapid global spread and human health impacts of SARS-CoV-2, the virus that causes
COVID-19, show humanity's vulnerability to zoonotic disease pandemics. Although …

Predicting the zoonotic capacity of mammals to transmit SARS-CoV-2

IR Fischhoff, AA Castellanos… - … of the Royal …, 2021 - royalsocietypublishing.org
Back and forth transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) between humans and animals will establish wild reservoirs of virus that endanger long …

Ecological conditions predict the intensity of Hendra virus excretion over space and time from bat reservoir hosts

DJ Becker, P Eby, W Madden, AJ Peel… - Ecology …, 2023 - Wiley Online Library
The ecological conditions experienced by wildlife reservoirs affect infection dynamics and
thus the distribution of pathogen excreted into the environment. This spatial and temporal …

Coinfections in wildlife: Focus on a neglected aspect of infectious disease epidemiology

AOG Hoarau, P Mavingui, C Lebarbenchon - PLoS Pathogens, 2020 - journals.plos.org
Emerging infectious diseases represent a global and major health problem. The
understanding of biological processes involved in the transmission and evolution of …

Selective replication and vertical transmission of Ebola virus in experimentally infected Angolan free-tailed bats

SA Riesle-Sbarbaro, G Wibbelt, A Düx… - Nature …, 2024 - nature.com
The natural reservoir of Ebola virus (EBOV), agent of a zoonosis burdening several African
countries, remains unidentified, albeit evidence points towards bats. In contrast, the ecology …

Bats generate lower affinity but higher diversity antibody responses than those of mice, but pathogen-binding capacity increases if protein is restricted in their diet

DE Crowley, CA Falvo, E Benson, J Hedges… - PLoS …, 2024 - journals.plos.org
Bats are reservoirs of many zoonotic viruses that are fatal in humans but do not cause
disease in bats. Moreover, bats generate low neutralizing antibody titers in response to …