Front‐loading is a drinking pattern in which alcohol intake is skewed toward the onset of
reward access. This phenomenon has been reported across several different alcohol self …

The development of animal models that demonstrate excessive levels of alcohol
consumption has played an important role in advancing our knowledge about …

Background Current models of compulsive‐like quinine‐adulterated alcohol (QuA) drinking
in mice, if improved, could be more useful for uncovering the neural mechanisms of …

Background Incentives to promote drinking (“happy hour”) can encourage faster rates of
alcohol consumption, especially in women. Sex differences in drinking dynamics may …

Background Previous research has demonstrated the utility of subanesthetic doses of
ketamine in decreasing binge (Drinking-in-the-Dark, or DID) 20% alcohol intake in female …

A key facet of alcohol use disorder is continuing to drink alcohol despite negative
consequences (so called “aversion-resistant drinking”). In this study, we sought to assess …

The timing, rate, and quantity of gestational alcohol consumption, collectively referred to
here as Maternal Drinking Patterns (MDPs), are of known importance to fetal developmental …

Background Excessive alcohol (ethanol) consumption, such as binge drinking, is extremely
commonplace and represents a major health concern. Through modeling excessive drinking …

Neural measures of alcohol cue incentive salience have been associated with retrospective
reports of riskier alcohol use behaviour and subjective response profiles. This study tested …

Baclofen is a GABA B receptor agonist with proposed use as a treatment for alcohol use
disorder (AUD). In preclinical studies, racemic baclofen decreases alcohol consumption in …