Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis

E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …

Biologic and small-molecule therapies for moderate-to-severe psoriasis: focus on psoriasis comorbidities

Y Jiang, Y Chen, Q Yu, Y Shi - BioDrugs, 2023 - Springer
Psoriasis is a systemic immune-mediated disease associated with an increased risk of
comorbidities, such as psoriatic arthritis, cardiovascular disease, metabolic syndrome …

Real-world practice indirect comparison between guselkumab, risankizumab, and tildrakizumab: results from an Italian 28-week retrospective study

M Megna, N Tommasino, L Potestio… - Journal of …, 2022 - Taylor & Francis
Background Guselkumab, tildrakizumab, and risankizumab, acting on interleukin (IL) 23
axis, have been recently approved for psoriasis management. However, real-life data …

Risankizumab treatment in psoriasis patients who failed anti‐IL17: a 52‐week real‐life study

M Megna, L Potestio, A Ruggiero… - Dermatologic …, 2022 - Wiley Online Library
Recent knowledge on the key role of interleukin (IL) 23/17 axis in psoriasis pathogenesis,
led to development of new biologic drugs. Risankizumab is a humanized immunoglobulin …

Depression, a major comorbidity of psoriatic disease, is caused by metabolic inflammation

U Mrowietz, M Sümbül, S Gerdes - Journal of the European …, 2023 - Wiley Online Library
Psoriatic disease is a chronic, systemic immune‐mediated inflammatory disorder comprising
three major domains, skin, vascular and bone/joint inflammation. It is known for a long time …

Towards personalized medicine in psoriasis: current progress

E Camela, L Potestio, A Ruggiero… - … : Targets and Therapy, 2022 - Taylor & Francis
Although innovative targeted therapies have positively revolutionized psoriasis treatment
shifting treatment goals to complete or almost complete skin clearance, primary or …

Risankizumab shows faster response in bio naïve than in bio‐experienced psoriatic patients.

L Mastorino, F Castelli, E Stroppiana… - Journal of the …, 2022 - search.ebscohost.com
This is because bio-naïve patients are candidates for biological treatment with a higher PASI
than bio-experienced patients who have taken risankizumab following initial secondary …

Exploring the association and causal effect between white blood cells and psoriasis using large-scale population data

G Zhou, X Ren, Z Tang, W Li, W Chen, Y He… - Frontiers in …, 2023 - frontiersin.org
Introduction Psoriasis is a chronic inflammatory disease of the skin. A few studies have
shown that psoriasis is an immune-mediated disease in which multiple immune cells play …

Effect of biological DMARDs and JAK inhibitors in pain of chronic inflammatory arthritis

A Alciati, M Di Carlo, C Siragusano… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The advent of biological disease‐modifying anti‐rheumatic drugs (bDMARDs)
and, more recently, of Janus kinase inhibitors (JAKi) has had a major impact on the long …

Hot topics: depression in individuals with psoriasis and psoriatic arthritis

N Goel, EB Wallace, C Lindsay - The Journal of Rheumatology, 2024 - jrheum.org
Psoriasis and psoriatic arthritis are associated with an increased risk of mental health
conditions such as depression and anxiety. People with psoriatic disease (PsD) are also …