Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

In the last decade, glycan microarrays have revolutionized the analysis of the specificity of
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …

The glycan structures of the receptor binding domain of the SARS‐CoV2 spike glycoprotein
expressed in human HEK293F cells have been studied by using NMR. The different …

Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …

A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell
surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan …

The beginning of the 20 th century marked the dawn of modern medicine with glycan-based
therapies at the forefront. However, glycans quickly became overshadowed as DNA-and …

Carbohydrate arrays, also referred to as glycan arrays, are composed of various
oligosaccharides and/or polysaccharides immobilized on a solid support in a spatially …

Siglecs (sialic acid immunoglobulin-like lectins) are members of the immunoglobulin gene
family that contain sialoside binding N-terminal domains. They are cell surface proteins …

Antibody-mediated cell depletion therapy has proven to provide significant clinical benefit in
treatment of lymphomas and leukemias, driving the development of improved therapies with …