Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

C Ke, KMV Narayan, JCN Chan, P Jha… - Nature Reviews …, 2022 - nature.com
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These
populations have an underlying predisposition to deficient insulin secretion, which has a key …

A review on semaglutide: an oral glucagon-like peptide 1 receptor agonist in management of type 2 diabetes mellitus

S Kalra, R Sahay - Diabetes Therapy, 2020 - Springer
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) are a well-established class of
glucose-lowering drugs. GLP-1 RAs can be classified according to their structure, duration of …

[HTML][HTML] The efficacy and safety of oral semaglutide for glycaemic management in adults with type 2 diabetes compared to subcutaneous semaglutide, placebo, and …

Y Alhindi, A Avery - Contemporary clinical trials communications, 2022 - Elsevier
Aim Semaglutide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1 RA)
indicated for glycaemic management in adults with type 2 diabetes (T2D). Oral semaglutide …

Incretin hormones in obesity and related cardiometabolic disorders: the clinical perspective

J Michałowska, E Miller-Kasprzak, P Bogdański - Nutrients, 2021 - mdpi.com
The prevalence of obesity continues to grow rapidly worldwide, posing many public health
challenges of the 21st century. Obese subjects are at major risk for serious diet-related …

Liraglutide pretreatment attenuates sepsis-induced acute lung injury

B Baer, ND Putz, K Riedmann… - … of Physiology-Lung …, 2023 - journals.physiology.org
There are no effective targeted therapies to treat acute respiratory distress syndrome
(ARDS). Recently, the commonly used diabetes and obesity medications, glucagon-like …

Glucagon-like peptide-1 receptor promotes osteoblast differentiation of dental pulp stem cells and bone formation in a zebrafish scale regeneration model

S Zhai, C Liu, S Vimalraj, R Subramanian, S Arora… - Peptides, 2023 - Elsevier
Bone cells express the glucagon-like peptide 1 receptor (GLP-1R). However, its presence
and role in human dental pulp derived stem cells (hDPSCs) remains elusive. Hence, in the …

Brain site-specific inhibitory effects of the GLP-1 analogue exendin-4 on alcohol intake and operant responding for palatable food

KJ Colvin, HS Killen, MJ Kanter, MC Halperin… - International Journal of …, 2020 - mdpi.com
Approximately 14.4 million Americans are experiencing alcohol use disorder (AUD) and
about two-thirds of people who experience drug addiction will relapse, highlighting the need …

Tirzepatide—Friend or Foe in Diabetic Cancer Patients?

SM Samuel, E Varghese, P Kubatka, D Büsselberg - Biomolecules, 2022 - mdpi.com
It is a well-accepted fact that obesity and diabetes increase the risk of incidence of different
cancers and their progression, leading to a decrease in the quality of life among affected …

Efficacy and safety of hydroxychloroquine as add-on therapy in uncontrolled type 2 diabetes patients who were using two oral antidiabetic drugs

HN Chakravarti, A Nag - Journal of endocrinological investigation, 2021 - Springer
Abstract Objective To evaluate the Safety and Efficacy of Hydroxychloroquine as add-on
therapy in uncontrolled type 2 diabetes patients who were using two oral antidiabetic drugs …

A review of oral semaglutide available evidence: A new era of management of diabetes with peptide in a pill form

S Kalra, S Das, AH Zargar - Indian Journal of Endocrinology and …, 2022 - journals.lww.com
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have gained an important place in
the management of diabetes management because of their exceptional glucose-lowering …