Strategies to overcome cancer multidrug resistance (MDR) through targeting P-glycoprotein (ABCB1): an updated review

J Dong, L Yuan, C Hu, X Cheng, JJ Qin - Pharmacology & Therapeutics, 2023 - Elsevier
The emergence of multidrug resistance (MDR) in malignant tumors is one of the leading
threats encountered currently in many chemotherapeutic agents. The overexpression of the …

Research status of dendrimer micelles in tumor therapy for drug delivery

X Wang, M Zhang, Y Li, H Cong, B Yu, Y Shen - Small, 2023 - Wiley Online Library
Dendrimers are a family of polymers with highly branched structure, well‐defined
composition, and extensive functional groups, which have attracted great attention in …

siRNA based drug design, quality, delivery and clinical translation

MA Subhan, VP Torchilin - Nanomedicine: Nanotechnology, Biology and …, 2020 - Elsevier
Gene silencing by RNA interference represents a promising therapeutic approach. The
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …

Micelle-engineered nanoplatforms for precision oncology

W Gao, A Bigham, M Ghomi, A Zarrabi… - Chemical Engineering …, 2024 - Elsevier
The alliance between nanomaterials and cancer therapy has revolutionized the treatment of
tumor patients. After cardiovascular diseases, cancer is the leading cause of death, so …

Advances in antibody nanoconjugates for diagnosis and therapy: A review of recent studies and trends

J Kadkhoda, M Akrami-Hasan-Kohal… - International journal of …, 2021 - Elsevier
Nowadays, the targeted imaging probe and drug delivery systems are the novel
breakthrough area in the nanomedicine and treatment of various diseases. Conjugation of …

[HTML][HTML] Delivery of therapeutic oligonucleotides in nanoscale

L Wu, W Zhou, L Lin, A Chen, J Feng, X Qu, H Zhang… - Bioactive materials, 2022 - Elsevier
Therapeutic oligonucleotides (TOs) represent one of the most promising drug candidates in
the targeted cancer treatment due to their high specificity and capability of modulating …

Doxorubicin-loaded micelles in tumor cell-specific chemotherapy

YQ Almajidi, MM Kadhim, F Alsaikhan, AT Jalil… - Environmental …, 2023 - Elsevier
Nanomedicine is a field that combines biology and engineering to improve disease
treatment, particularly in cancer therapy. One of the promising techniques utilized in this …

Effect of surface ligand modification on the properties of anti-tumor nanocarrier

N Ying, X Lin, M Xie, D Zeng - Colloids and Surfaces B: Biointerfaces, 2022 - Elsevier
With the continuous increasing number of cancer patients worldwide, there has been great
interest in developing the targeted delivery anti-cancer drugs. The drug concentration …

Overcoming doxorubicin resistance in cancer: siRNA-loaded nanoarchitectures for cancer gene therapy

MDA Paskeh, H Saebfar, MK Mahabady, S Orouei… - Life Sciences, 2022 - Elsevier
Gene therapy can be used as a cancer therapy by affecting signaling networks participating
in the aggressive behavior of tumors. Small interfering RNA (siRNA) is a genetic tool …

Antibody-modified DNase I micelles specifically recognize the neutrophil extracellular traps (NETs) and promote their degradation

N Filipczak, X Li, GR Saawant, SSK Yalamarty… - Journal of Controlled …, 2023 - Elsevier
Neutrophil extracellular traps (NETs) are structures consisting of decondensed chromatin
with associated proteins, including histones and antimicrobial peptides, released from …