Cancer stands as a serious malady, posing substantial risks to human well‐being and
survival. This underscores the paramount necessity to explore and investigate novel …

Receptor tyrosine kinases (RTKs) are a class of protein kinases that play crucial roles in
various cellular processes, including cell migration, morphological differentiation, cell …

Aims The cellular defense system against oxidative stress is important for the survival ability
and sensitization in chemotherapy; however, the regulatory mechanisms remain unknown in …

Recent research has shown that cyclin dependent kinase 7 (CDK7), cyclin dependent
kinase 9 (CDK9) and cyclin T1 (CCNT1) can assist transcriptional misregulation in cancer …

Triple-negative breast cancer (TNBC) comprises a group of aggressive and heterogeneous
breast carcinoma. Chemotherapy is the mainstay for the treatment of triple-negative tumors …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor prognosis. The
number of cases increased by 2.26 million in 2020, making it the most commonly diagnosed …

Abstract Y‑box binding protein‑1 (YB-1) is a multifunctional protein that is highly expressed
in human solid tumors of various entities. Several cellular processes, eg cell cycle …

Neoadjuvant chemotherapy (NAC) is a well-established treatment modality for locally
advanced breast cancer (BC). However, it can also result in severe toxicities while …

Androgen has been shown to regulate male physiological activities and cancer proliferation.
It is used to antagonize estrogen-induced proliferative effects in breast cancer cells …

The spreading of cancer cells from the primary tumor site to other parts of the body, known
as metastasis, is the leading cause of cancer recurrence and mortality in patients with triple …