Principles and requirements for stroke recovery science

CJ Sommer, WR Schäbitz - Journal of Cerebral Blood Flow & …, 2021 - journals.sagepub.com
The disappointing results in bench-to-bedside translation of neuroprotective strategies
caused a certain shift in stroke research towards enhancing the endogenous recovery …

Non-human primate models of focal cortical ischemia for neuronal replacement therapy

J Mu, P Hao, H Duan, W Zhao… - Journal of Cerebral …, 2023 - journals.sagepub.com
Despite the high prevalence, stroke remains incurable due to the limited regeneration
capacity in the central nervous system. Neuronal replacement strategies are highly diverse …

Changes in cortical manifold structure following stroke and its relation to behavioral recovery in the male macaque

JY Nashed, DJ Gale, JP Gallivan, DJ Cook - Nature Communications, 2024 - nature.com
Stroke, a major cause of disability, disrupts brain function and motor skills. Previous
research has mainly focused on reorganization of the motor system post-stroke, but the …

A non-human primate model of stroke reproducing endovascular thrombectomy and allowing long-term imaging and neurological read-outs

J Debatisse, O Wateau, TH Cho… - Journal of Cerebral …, 2021 - journals.sagepub.com
Stroke is a devastating disease. Endovascular mechanical thrombectomy is dramatically
changing the management of acute ischemic stroke, raising new challenges regarding brain …

Intranasal salvinorin A improves neurological outcome in rhesus monkey ischemic stroke model using autologous blood clot

L Wu, D Wu, J Chen, C Chen, T Yao… - Journal of Cerebral …, 2021 - journals.sagepub.com
Salvinorin A (SA) exerts neuroprotection and improves neurological outcomes in ischemic
stroke models in rodents. In this study, we investigated whether intranasal SA administration …

A reproducible new model of focal ischemic injury in the marmoset monkey: MRI and behavioural follow-up

A Le Friec, F Desmoulin, B Demain, C Davoust… - Translational Stroke …, 2021 - Springer
Ischemic stroke mostly affects the primary motor cortex and descending motor fibres, with
consequent motor impairment. Pre-clinical models of stroke with reproducible and long …

The brain–bone axis: unraveling the complex interplay between the central nervous system and skeletal metabolism

H Shi, M Chen - European Journal of Medical Research, 2024 - Springer
The brain–bone axis has emerged as a captivating field of research, unveiling the intricate
bidirectional communication between the central nervous system (CNS) and skeletal …

Consistent spatial lesion-symptom patterns: A comprehensive analysis using triangulation in lesion-symptom mapping in a cohort of stroke patients

G Ramirez-Garcia, X Escutia-Macedo, DJ Cook… - Magnetic Resonance …, 2024 - Elsevier
Introduction The relationship between brain lesions and stroke outcomes is crucial for
advancing patient prognosis and developing effective therapies. Stroke is a leading cause of …

[引用][C] 缺血性脑卒中非人灵长类动物模型研究进展

孙宇航, 管博文, 魏强, 孟爱民 - 中国比较医学杂志, 2022