Objectives Despite the current pneumococcal vaccination program in England for older
adults and adults with underlying conditions, disease burden remains high. We evaluated …

Infections caused by Streptococcus pneumoniae (also known as pneumococci) pose a
threat to human health. Pneumococcal infections are the most common cause of milder …

Background A new 20-valent pneumococcal conjugate vaccine (PCV20) provides protection
against 20 pneumococcal serotypes. The vaccine has the potential to decrease the impact of …

Streptococcus pneumoniae is a major cause of community-acquired pneumonia,
bacteremia, and meningitis in older adults worldwide. Two pneumococcal vaccines …

The increasing recent interest in human challenge studies or controlled human infection
model studies for accelerating vaccine development has been driven by the recognition of …

Inadequate menstrual hygiene management (MHM) practices have been associated with
adverse health outcomes. This study aimed to describe MHM practices among schoolgirls …

Objectives: Streptococcus pneumoniae is the leading bacterial pathogen causing respiratory
infections. Since the COVID-19 pandemic emerged, less invasive pneumococcal disease …

Introduction Immunosenescence is a normal biologic process involving deterioration of
protective immune responses. Consequently, older adults experience increased risk of …

Streptococcus pneumoniae colonization in the upper respiratory tract is linked to
pneumococcal disease development, predominantly affecting young children and older …

Purpose: To investigate the baseline levels of serotype-specific IgG antibodies to
Streptococcus pneumoniae (S. pneumoniae) and assess their impact on the assessment of …