Objective: To estimate the current incidence and prevalence in the United States of 12
neurologic disorders. Methods: We summarize the strongest evidence available, using data …

Background: In 1991, the first world survey of neuromuscular disorders (NMDs) was
published in the peer reviewed literature. Since then, diagnostics have been greatly …

Background The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently
reported as 10%. However, a systematic review and meta-analysis of the true population …

Abstract Background/Aims: We aimed to estimate the incidence and prevalence of
amyotrophic lateral sclerosis (ALS) in the South East of England. The reported incidence of …

Objective: To determine the incidence, prevalence, and mortality rates of ALS in the province
of Modena, Northern Italy, from 1990 through 1999. Methods: A retrospective epidemiologic …

The identity and role of environmental factors in the etiology of sporadic amyotrophic lateral
sclerosis (sALS) is poorly understood outside of three former high-incidence foci of Western …

OBJECTIVES: To assess the epidemiologic characteristics of amyotrophic lateral sclerosis
(ALS) in Brazil in 1998. METHOD: Structured Clinical Report Forms (CRFs) sent to 2,505 …

Amyotrophic lateral sclerosis (ALS) has a fatal outcome in about three years, but survival is
known to vary considerably, making it difficult to predict disease duration in individual cases …

Recent genetic studies suggest a Sardinian type of amyotrophic lateral sclerosis (ALS).
Thus, ALS incidence, prevalence and survival were investigated in a large population of …

The diagnosis of sALS and fALS in the individual requires both recognition of clinical signs
and analysis of the signs and symptoms in order to provide the certainty of the diagnosis …