Endothelial ROBO4 suppresses PTGS2/COX-2 expression and inflammatory diseases

M Tanaka, K Shirakura, Y Takayama, M Μatsui… - Communications …, 2024 - nature.com
Accumulating evidence suggests that endothelial cells can be useful therapeutic targets.
One of the potential targets is an endothelial cell-specific protein, Roundabout4 (ROBO4) …

Efficacy and safety of preoperative versus postoperative NSAIDs on pain relief in patients undergoing hip arthroscopy surgery: A multicentre, randomized, controlled …

W Zhang, Q Zhao, G Yang, N Han… - Journal of Clinical …, 2022 - Wiley Online Library
What is known and objective Postoperative pain relief is a critical issue for hip arthroscopy
surgery (HAS). This study aimed to investigate the effect of preemptive non‐steroidal anti …

[PDF][PDF] Design of 1, 4-Dihydropyridine hybrid benzamide derivatives: synthesis and evaluation of analgesic activity and their molecular docking studies

I Akbar, S Radhakrishnan… - Drug Design …, 2022 - Taylor & Francis
Purpose This study aims to determine the analgesic activity of 1, 4-dihydropyridine hybrid
benzamide derivatives. These hybrid derivatives were synthesized, and their analgesic …

[PDF][PDF] Nitridergic Modulation of COX-2 Efficacy

H Miranda, V Noriega, F Moreno, F Sierralta… - 2022 - repositorio.udd.cl
Pain is a common unpleasant sensory and emotional experience, in which are frequently
used in their treatment the nonsteroidal anti-inflammatory drugs (NSAIDs). A group of agents …

[PDF][PDF] ДИТЕРПЕНОВЫЕ АЛКАЛОИДЫ АКОНИТИНОВОГО И АТИЗИНОВОГО РЯДА КАК ОСНОВА ПЕРСПЕКТИВНЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ

ТН Поветьева, ГН Зюзьков - tnimc.ru
В последние десятилетия удалось достичь больших успехов в развитии фармакологии
и фармации. Разработаны препараты на основе эндогенных регуляторов функций и их …