Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

The proceeding pandemic of coronavirus disease 2019 is the latest global challenge. Like
most other infectious diseases, inflammation, oxidative stress, and immune system …

Abstract SARS CoV-2 nonstructural protein 1 (Nsp1) is the major pathogenesis factor that
inhibits host translation using a dual strategy of impairing initiation and inducing …

To facilitate selfish replication, viruses halt host gene expression in various ways. The
nuclear export of mRNA is one such process targeted by many viruses. SARS-CoV-2, the …

Abstract SARS-Cov-2 infection, which has caused the COVID-19 global pandemic, triggers
cellular senescence. In this study, we investigate the role of the SARS-COV-2 spike protein …

Abstract Corona Virus Disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), poses a serious threat to human health and life …

Central nervous system (CNS) pathologies are a public health concern, with viral infections
one of their principal causes. These viruses are known as neurotropic pathogens …

Inducible promoters are one of cellular and molecular biology's most important technical
tools. The ability to deplete, replete, and overexpress genes on demand is the foundation of …

Coronavirus disease 2019 (COVID-19), an infectious acute respiratory disease caused by a
newly emerging RNA virus, is a still-growing pandemic that has caused more than 6 million …

Abstract Upon SARS-CoV-2 infection, patients with severe forms of COVID-19 often suffer
from a dysregulated immune response and hyperinflammation. Aberrant expression of …