Cancer is a black spot on the face of humanity in this era of science and technology.
Presently, several classes of anticancer drugs are available in the market, but issues such …

Transition Metal-Mediated Synthesis of Monocyclic Aromatic Heterocycles | Chemical Reviews
ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

At the advent of cross-coupling chemistry, carbon electrophiles based on halides or
pseudohalides were the only suitable electrophilic coupling partners. Almost two decades …

Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

A direct synthesis of carbaldehydes through intramolecular dehydrogenative
aminooxygenation has been developed. The process uses a catalytic amount of copper (II) …

Overexpression of the antiapototic proteins Bcl-2 and Bcl-xL provides a common mechanism
through which cancer cells gain a survival advantage and become resistant to conventional …

A simple, modular method to prepare highly substituted pyridines is disclosed. The method
employs a cascade reaction comprising (1) a novel N-iminative, Cu-catalyzed cross …

A palladium-catalyzed domino aminopalladation/CH functionalization sequence has been
developed, and provides access to functionalized phenanthridines and isoquinolines. The …

Copper-catalyzed coupling of oxime acetates with aldehydes offers a new strategy for the
synthesis of highly substituted pyridines. This novel method tolerates a wide range of …

A nickel-catalyzed 1, 2-aminoarylation of oxime-ester-tethered alkenes with boronic acids
was developed. A variety of pyrroline derivatives were synthesized in good yields via the …