Navigating the dementia landscape: Biomarkers and emerging therapies

S Maheshwari, A Singh, VA Ansari, T Mahmood… - Ageing Research …, 2024 - Elsevier
The field of dementia research has witnessed significant developments in our understanding
of neurodegenerative disorders, with a particular focus on Alzheimer's disease (AD) and …

Role of regulatory non-coding RNAs in traumatic brain injury

S Li, N Qiu, A Ni, MH Hamblin, KJ Yin - Neurochemistry international, 2024 - Elsevier
Traumatic brain injury (TBI) is a potentially fatal health event that cannot be predicted in
advance. After TBI occurs, it can have enduring consequences within both familial and …

Connexin43 promotes angiogenesis through activating the HIF-1α/VEGF signaling pathway under chronic cerebral hypoperfusion

W Yu, H Jin, W Sun, D Nan, J Deng… - Journal of Cerebral …, 2021 - journals.sagepub.com
Chronic cerebral hypoperfusion, a major vascular contributor to vascular cognitive
impairment and dementia, can exacerbate small vessel pathology. Connexin43, the most …

Genetic deficiency of MicroRNA‐15a/16‐1 confers resistance to neuropathological damage and cognitive dysfunction in experimental vascular cognitive impairment …

C Zhou, P Sun, Y Xu, Y Chen, Y Huang… - Advanced …, 2022 - Wiley Online Library
Chronic cerebral hypoperfusion‐derived brain damage contributes to the progression of
vascular cognitive impairment and dementia (VCID). Cumulative evidence has shown that …

Dementia and metabolic syndrome: a bibliometric analysis

T Peng, Y Yang, J Ma, P Xu, X Xie, N Hu… - Frontiers in Aging …, 2024 - frontiersin.org
Background Dementia is a progressive neurodegenerative condition, while metabolic
syndrome (MetS) is characterized by a combination of metabolic abnormalities such as …

Non-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders

P Sun, MH Hamblin, KJ Yin - Fluids and barriers of the CNS, 2022 - Springer
The blood–brain barrier (BBB) is an essential component of the neurovascular unit that
controls the exchanges of various biological substances between the blood and the brain …

Sonic Hedgehog Signalling Pathway Contributes in Age-Related Disorders and Alzheimer's Disease

A Parashar, V Mehta, B Chauhan, P Ghosh… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is caused by the aging process and manifested by cognitive
deficits and progressive memory loss. During aging, several conditions, including …

Biomarkers of frailty: miRNAs as common signatures of impairment in cognitive and physical domains

S Dato, P Crocco, F Iannone, G Passarino, G Rose - Biology, 2022 - mdpi.com
Simple Summary A growing number of studies have focused their attention on the potential
role of microRNAs (miRNA) as biomarkers for several diseases. However, very few …

A Review on Tau Targeting Biomimetics Nano Formulations: Novel Approach for Targeting Alzheimer's Diseases

A Singh, S Maheshwari, JP Yadav… - … System Agents in …, 2024 - benthamdirect.com
Central nervous system disorders are prevalent, profoundly debilitating, and poorly
managed. Developing innovative treatments for these conditions, including Alzheimer's …

Administration of rTMS alleviates stroke-induced cognitive deficits by modulating miR-409-3p/CTRP3/AMPK/Sirt1 Axis

T Wu, C Tang, J Fan, J Tao - Journal of Molecular Neuroscience, 2022 - Springer
Cognitive deficit is a typical complication induced by stroke injuries. Repetitive transcranial
magnetic stimulation (rTMS) is a technique that can both attenuate neuropsychiatric …