Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve

CHK Hughes, OE Smith… - Proceedings of the …, 2023 - National Acad Sciences
The ovarian follicle reserve, formed pre-or perinatally, comprises all oocytes for lifetime
reproduction. Depletion of this reserve results in infertility. Steroidogenic factor 1 (SF-1; …

A single-cell atlas of the cycling murine ovary

ME Morris, MC Meinsohn, M Chauvin, HD Saatcioglu… - Elife, 2022 - elifesciences.org
The estrous cycle is regulated by rhythmic endocrine interactions of the nervous and
reproductive systems, which coordinate the hormonal and ovulatory functions of the ovary …

Follicular development and ovary aging: single-cell studies

H Zhao, Y Wang, Y Yang - Biology of Reproduction, 2023 - academic.oup.com
Follicular development is a critical process in reproductive biology that determines the
number of oocytes and interacts with various cells within the follicle (such as oocytes …

Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene

LM Vansandt, MC Meinsohn, P Godin… - Nature …, 2023 - nature.com
Eighty percent of the estimated 600 million domestic cats in the world are free-roaming.
These cats typically experience suboptimal welfare and inflict high levels of predation on …

Anti-Mullerian hormone attenuates both cyclophosphamide-induced damage and PI3K signalling activation, while rapamycin attenuates only PI3K signalling …

R Rosario, HL Stewart, N Spears, EE Telfer… - Human …, 2024 - academic.oup.com
STUDY QUESTION What are the effects of cyclophosphamide exposure on the human ovary
and can anti-Mullerian hormone (AMH) and rapamycin protect against these? SUMMARY …

Potential Role of Anti-Müllerian Hormone in Regulating Seasonal Reproduction in Animals: The Example of Males

K An, B Yao, Y Tan, Y Kang, J Su - International Journal of Molecular …, 2023 - mdpi.com
Seasonal reproduction is a survival strategy by which animals adapt to environmental
changes to improve their fitness. Males are often characterized by a significantly reduced …

A single-cell atlas of the aging mouse ovary

JVV Isola, SR Ocañas, CR Hubbart, S Ko, SA Mondal… - Nature Aging, 2024 - nature.com
Ovarian aging leads to diminished fertility, dysregulated endocrine signaling and increased
chronic disease burden. These effects begin to emerge long before follicular exhaustion …

[HTML][HTML] Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis

M Chauvin, MC Meinsohn, S Dasari, P May, S Iyer… - Cell Reports, 2023 - cell.com
Cancer-associated mesothelial cells (CAMCs) in the tumor microenvironment are thought to
promote growth and immune evasion. We find that, in mouse and human ovarian tumors …

Anti-Müllerian hormone-mediated preantral follicle atresia is a key determinant of antral follicle count in mice

Y Zhou, S Richard, NJ Batchelor… - Human …, 2022 - academic.oup.com
Abstract STUDY QUESTION Does anti-Müllerian hormone (AMH) induce preantral follicle
atresia in mice? SUMMARY ANSWER The present findings suggest that AMH-mediated …

Single-cell RNA sequencing analysis of mouse follicular somatic cells

S Li, LN Chen, HJ Zhu, X Feng, FY Xie… - Biology of …, 2021 - academic.oup.com
Within the development of ovarian follicle, in addition to cell proliferation and differentiation,
sophisticated cell–cell cross talks are established among follicular somatic cells such as …